Title | Orthogonal Access to alpha-/beta-Branched/Linear Aliphatic Amines by Catalyst-Tuned Regiodivergent Hydroalkylations |
Author | |
Corresponding Author | Shu, Wei |
Publication Years | 2022-07-01
|
DOI | |
Source Title | |
ISSN | 1433-7851
|
EISSN | 1521-3773
|
Abstract | Linear, alpha-branched, and beta-branched aliphatic amines are widespread in pharmaceuticals, agrochemicals, and fine chemicals. Thus, the development of direct and efficient methods to these structures in a tunable manner is highly desirable yet challenging. Herein, a catalyst-controlled synthesis of alpha-branched, beta-branched and linear aliphatic amines from Ni/Co-catalyzed regio- and site-selective hydroalkylations of alkenyl amines with alkyl halides is developed. This catalytic protocol features the reliable prediction and control of the coupling position of alkylation to provide orthogonal access to alpha-branched, beta-branched and linear alkyl amines from identical starting materials. This platform unlocks orthogonal reactivity and selectivity of nickel hydride and cobalt hydride chemistry to catalytically repurpose three types of alkyl amines under mild conditions. |
Keywords | |
URL | [Source Record] |
Indexed By | |
Language | English
|
Important Publications | NI Journal Papers
|
SUSTech Authorship | First
; Corresponding
|
Funding Project | NSFC[
|
WOS Research Area | Chemistry
|
WOS Subject | Chemistry, Multidisciplinary
|
WOS Accession No | WOS:000823858300001
|
Publisher | |
EI Accession Number | 20222912365282
|
EI Keywords | Agricultural chemicals
; Catalysts
; Cobalt compounds
; Hydrides
; Nickel compounds
|
ESI Classification Code | Chemical Agents and Basic Industrial Chemicals:803
; Chemical Products Generally:804
; Organic Compounds:804.1
; Inorganic Compounds:804.2
; Agricultural Chemicals:821.2
|
ESI Research Field | CHEMISTRY
|
Data Source | Web of Science
|
Publication Status | 正式出版
|
Citation statistics |
Cited Times [WOS]:18
|
Document Type | Journal Article |
Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/355826 |
Department | Department of Chemistry 深圳格拉布斯研究院 |
Affiliation | 1.Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Dept Chem, Shenzhen 518055, Guangdong, Peoples R China 2.Southern Univ Sci & Technol, Guangdong Prov Key Lab Catalysis, Shenzhen 518055, Guangdong, Peoples R China 3.Nankai Univ, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China |
First Author Affilication | Department of Chemistry; Shenzhen Grubbs Institute; Southern University of Science and Technology |
Corresponding Author Affilication | Department of Chemistry; Shenzhen Grubbs Institute; Southern University of Science and Technology |
First Author's First Affilication | Department of Chemistry; Shenzhen Grubbs Institute |
Recommended Citation GB/T 7714 |
Yang, Peng-Fei,Shu, Wei. Orthogonal Access to alpha-/beta-Branched/Linear Aliphatic Amines by Catalyst-Tuned Regiodivergent Hydroalkylations[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2022.
|
APA |
Yang, Peng-Fei,&Shu, Wei.(2022).Orthogonal Access to alpha-/beta-Branched/Linear Aliphatic Amines by Catalyst-Tuned Regiodivergent Hydroalkylations.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION.
|
MLA |
Yang, Peng-Fei,et al."Orthogonal Access to alpha-/beta-Branched/Linear Aliphatic Amines by Catalyst-Tuned Regiodivergent Hydroalkylations".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2022).
|
Files in This Item: | ||||||
File Name/Size | DocType | Version | Access | License | ||
ACIE-2022, 61, e2022(10938KB) | Restricted Access | -- |
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