Comparison of the Effects of Three Different Methods in the Treatment of Intercostal Postherpetic Neuralgia

Zhang, Zhenwu; Ling, Diyang; Wu, Qiong; Zhao, Yan; Zhang, Juan; Wang, Zheyin

2021-12-01

Analytical and Quantitative Cytopathology and Histopathology   Impact Factor & Quartile

0884-6812

["OBJECTIVE: To investigate the therapeutic effects of simple drug therapy, B-ultrasound guided paraverte-bral block (PVB), and plasma thermocoagulation of dor-sal root ganglion (DRG) in the treatment of intercostal postherpetic neuralgia (iPHN).","STUDY DESIGN: A total of 120 patients with acute iPHN were divided into oral administration therapy group (group A), thoracic paravertebral block (TPVB) therapy group (group B), and DRG block combined with low-temperature plasma thermocoagulation ther-apy group (group C). Group A was treated with anti-viral therapy combined with analgesic drugs, group B with B-ultrasound-guided TPVB on the basis of group A, and group C with DRG block combined with low-temperature plasma thermocoagulation on the basis of group A. We analyzed the pain scores by using numeric rating scales (NRSs) at weeks 1, 2, 3, and 4 after treat-ment and sleep quality at weeks 2 and 4 after treatment. Finally, the drug-related adverse reactions or complica-tions were recorded.","RESULTS: At weeks 1, 2, 3, and 4 after treatment the NRS scores of groups B and C were significantly lower than that of group A, and the NRS score of group C was slightly lower than that of group B. The difference was statistically significant. After weeks 2 and 4 of treat-ment, the sleep quality of groups B and C were promi-nently better than that of group A, and the sleep quality of group C was better than that of group B; the differ-ence was statistically significant. There were no post-operative complications in groups B and C. However, some patients in group C experienced hypoesthesia in the skin that received thermocoagulation, but no influ-ence on life and no painful numbness. Collectively, no significant difference was identified in the incidence of adverse reactions or complications among the 3 groups.","CONCLUSION: All 3 treatment methods have cer-tain clinical efficacy for iPHN, which can effectively relieve the pain caused by herpes zoster and improve sleep. Among them, DGR block combined with low-temperature plasma thermocoagulation may have better clinical application significance."]

herpes zoster intercostal postherpetic neuralgia low-temperature plasma thermocoagulation nerve block oral administration shingles

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Cell Biology

Cell Biology

WOS:000825538700001

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1.Jinan Univ, Clin Med Coll 2, Shenzhen Peoples Hosp, Dept Pain, Shenzhen, Guangdong, Peoples R China
2.Southern Univ Sci & Technol, Affiliated Hosp 1, Shenzhen, Guangdong, Peoples R China

Zhang, Zhenwu,Ling, Diyang,Wu, Qiong,et al. Comparison of the Effects of Three Different Methods in the Treatment of Intercostal Postherpetic Neuralgia[J]. Analytical and Quantitative Cytopathology and Histopathology,2021,43(6).

Zhang, Zhenwu,Ling, Diyang,Wu, Qiong,Zhao, Yan,Zhang, Juan,&Wang, Zheyin.(2021).Comparison of the Effects of Three Different Methods in the Treatment of Intercostal Postherpetic Neuralgia.Analytical and Quantitative Cytopathology and Histopathology,43(6).

Zhang, Zhenwu,et al."Comparison of the Effects of Three Different Methods in the Treatment of Intercostal Postherpetic Neuralgia".Analytical and Quantitative Cytopathology and Histopathology 43.6(2021).