Ultrafast construction of partially hydrogen-bonded metal-hyaluronan networks with multiple biotissue-related features
This paper reports a versatile and dynamic hydrogel system based on ultrafast coordination between partially hydrogen-bonded (PHB) biopolymer hyaluronic acid and a series of transition metal ions at appropriate pH values. It was found that the procedure for the hydrogel synthesis was extremely facile, requiring a simple mixing of the components within 2 s. The hydrogels exhibited high water content, up to 96 %. Even so, the hydrogels can be stretched >50 times and rapidly self-heal from damage within only 10 s without using any healing agents or heating. Furthermore, this dynamic hydrogel network underwent reversible sol-gel transitions as response to multiple disparate stimuli, including pH, temperature, ions, redox, and light. The photo-patterning ability of the hydrogel with a rapid gel-sol transition upon exposure to light was also demonstrated. We disclosed the principle and methodology to use PHB metal-biopolymer systems for constructing dynamic bio-related soft matters.
National Natural Science Foundation of China;National Natural Science Foundation of China;
|EI Accession Number|
Biomolecules ; Biopolymers ; Hyaluronic acid ; Hydrogels ; Hydrogen ; Metal ions ; Organic acids ; Self-healing materials ; Sol-gels ; Transition metal compounds ; Transition metals
|ESI Classification Code|
Metals, Plastics, Wood and Other Structural Materials:415 ; Biological Materials and Tissue Engineering:461.2 ; Biology:461.9 ; Metallurgy and Metallography:531 ; Metallurgy:531.1 ; Biochemistry:801.2 ; Colloid Chemistry:801.3 ; Physical Chemistry:801.4 ; Chemical Products Generally:804 ; Organic Compounds:804.1 ; Polymeric Materials:815.1
|ESI Research Field|
Cited Times [WOS]:4
|Document Type||Journal Article|
|Department||Department of Materials Science and Engineering|
1.School of Chemistry and Chemical Engineering,Anyang Normal University,Anyang,Anyang,455000,China
2.Department of Materials Science and Engineering,Shenzhen Key Laboratory of Interfacial Science and Engineering of Materials,Southern University of Science and Technology,Shenzhen,518055,China
|Corresponding Author Affilication||Department of Materials Science and Engineering|
Sun，Zhifang,Lyu，Fucong,Wu，Shaofei,et al. Ultrafast construction of partially hydrogen-bonded metal-hyaluronan networks with multiple biotissue-related features[J]. CARBOHYDRATE POLYMERS,2022,295.
Sun，Zhifang,Lyu，Fucong,Wu，Shaofei,Lu，Zhouguang,&Cheng，Hua.(2022).Ultrafast construction of partially hydrogen-bonded metal-hyaluronan networks with multiple biotissue-related features.CARBOHYDRATE POLYMERS,295.
Sun，Zhifang,et al."Ultrafast construction of partially hydrogen-bonded metal-hyaluronan networks with multiple biotissue-related features".CARBOHYDRATE POLYMERS 295(2022).
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