Title | Highly efficient synthesis of chiral β-amino phosphine derivatives via direct asymmetric reductive amination with ammonium salts and H2 |
Author | |
Corresponding Author | Ma,Baode; Zhang,Xumu |
Publication Years | 2022-06-24
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DOI | |
Source Title | |
EISSN | 2666-5549
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Volume | 3Issue:3 |
Abstract | A highly efficient and enantioselective method for the asymmetric reductive amination of β-keto phosphine derivatives was disclosed, and the corresponding β-amino phosphine oxides could be obtained in high yields (up to 97% yield) and excellent enantioselectivities (up to 97% ee). Moreover, the reaction worked well on a gram scale, indicating that our protocol has potential applications in the synthesis of chiral ligands and organocatalysts. |
Keywords | |
URL | [Source Record] |
Indexed By | |
Language | English
|
SUSTech Authorship | First
; Corresponding
|
Funding Project | National Natural Science Foundation of China[21901107]
; National Natural Science Foundation of China["21901107","2020B010188001","2022B1515020055"]
; Shenzhen Bay Laboratory[22171129]
; Shenzhen Science and Technology Innovation Committee["22001113","2020KCXTD016"]
; Key-Area Research and Development Program of Guangdong Province[SZBL2019062801006]
; Stable Support Plan Program of Shenzhen Science and Technology Innovation Committee[KQTD20150717103157174]
; Innovative Team of Universities in Guangdong Province[JCYJ20210324104202007]
; Guangdong Basic and Applied Basic Research Foundation[20200925161222002]
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WOS Research Area | Chemistry
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WOS Subject | Chemistry, Multidisciplinary
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WOS Accession No | WOS:001025341600001
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Publisher | |
Data Source | Web of Science
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Citation statistics |
Cited Times [WOS]:3
|
Document Type | Journal Article |
Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/359574 |
Department | Department of Chemistry 前沿与交叉科学研究院 |
Affiliation | 1.Medi-X Pingshan,Guangdong Provincial Key Laboratory of Catalysis,and Department of Chemistry,Southern University of Science and Technology,Shenzhen,518000,China 2.Shenzhen Bay Laboratory,Shenzhen,518132,China 3.Academy for Advanced Interdisciplinary Studies and Southern University of Science and Technology,Shenzhen,518000,China |
First Author Affilication | Department of Chemistry |
Corresponding Author Affilication | Department of Chemistry |
First Author's First Affilication | Department of Chemistry |
Recommended Citation GB/T 7714 |
Liu,Yufeng,Wang,Linzhou,Li,Yingjun,et al. Highly efficient synthesis of chiral β-amino phosphine derivatives via direct asymmetric reductive amination with ammonium salts and H2[J]. Green Synthesis and Catalysis,2022,3(3).
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APA |
Liu,Yufeng,Wang,Linzhou,Li,Yingjun,Ma,Baode,Chen,Gen Qiang,&Zhang,Xumu.(2022).Highly efficient synthesis of chiral β-amino phosphine derivatives via direct asymmetric reductive amination with ammonium salts and H2.Green Synthesis and Catalysis,3(3).
|
MLA |
Liu,Yufeng,et al."Highly efficient synthesis of chiral β-amino phosphine derivatives via direct asymmetric reductive amination with ammonium salts and H2".Green Synthesis and Catalysis 3.3(2022).
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