中文版 | English
Title

Dysfunction of histone demethylase IBM1 in Arabidopsis causes autoimmunity and reshapes the root microbiome

Author
Corresponding AuthorZhang, Huiming
Joint first authorLv, Suhui; Yang, Yu; Yu, Gang
Publication Years
2022-07-01
DOI
Source Title
ISSN
1751-7362
EISSN
1751-7370
Abstract

Root microbiota is important for plant growth and fitness. Little is known about whether and how the assembly of root microbiota may be controlled by epigenetic regulation, which is crucial for gene transcription and genome stability. Here we show that dysfunction of the histone demethylase IBM1 (INCREASE IN BONSAI METHYLATION 1) in Arabidopsis thaliana substantially reshaped the root microbiota, with the majority of the significant amplicon sequence variants (ASVs) being decreased. Transcriptome analyses of plants grown in soil and in sterile growth medium jointly disclosed salicylic acid (SA)-mediated autoimmunity and production of the defense metabolite camalexin in the ibm1 mutants. Analyses of genome-wide histone modifications and DNA methylation highlighted epigenetic modifications permissive for transcription at several important defense regulators. Consistently, ibm1 mutants showed increased resistance to the pathogen Pseudomonas syringae DC3000 with stronger immune responses. In addition, ibm1 showed substantially impaired plant growth promotion in response to beneficial bacteria; the impairment was partially mimicked by exogenous application of SA to wild-type plants, and by a null mutation of AGP19 that is important for cell expansion and that is repressed with DNA hypermethylation in ibm1. IBM1-dependent epigenetic regulation imposes strong and broad impacts on plant-microbe interactions and thereby shapes the assembly of root microbiota.

URL[Source Record]
Indexed By
Language
English
Important Publications
NI Journal Papers
SUSTech Authorship
Others
Funding Project
National Natural Science Foundation of China[NSFC-31801086]
WOS Research Area
Environmental Sciences & Ecology ; Microbiology
WOS Subject
Ecology ; Microbiology
WOS Accession No
WOS:000833452500001
Publisher
Data Source
Web of Science
Citation statistics
Cited Times [WOS]:4
Document TypeJournal Article
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/365014
DepartmentDepartment of Biology
Affiliation
1.Chinese Acad Sci, Shanghai Ctr Plant Stress Biol, Ctr Excellence Mol Plant Sci, Shanghai 201602, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Shanghai Chenshan Bot Garden, Shanghai Key Lab Plant Funct Genom & Resources, Shanghai 201602, Peoples R China
4.Fujian Agr & Forestry Univ, Haixia Inst Sci & Technol, Fuzhou 350002, Peoples R China
5.Southern Univ Sci & Technol, Dept Biol, Shenzhen 518055, Peoples R China
6.Purdue Univ, Dept Hort & Landscape Architecture, W Lafayette, IN USA
7.Inst Tecnol Quim & Biol ITQB, Lisbon, Portugal
8.Shoolini Univ, Appl Sci & Biotechnol, Solan 173212, India
Recommended Citation
GB/T 7714
Lv, Suhui,Yang, Yu,Yu, Gang,et al. Dysfunction of histone demethylase IBM1 in Arabidopsis causes autoimmunity and reshapes the root microbiome[J]. ISME Journal,2022.
APA
Lv, Suhui.,Yang, Yu.,Yu, Gang.,Peng, Li.,Zheng, Shuai.,...&Zhang, Huiming.(2022).Dysfunction of histone demethylase IBM1 in Arabidopsis causes autoimmunity and reshapes the root microbiome.ISME Journal.
MLA
Lv, Suhui,et al."Dysfunction of histone demethylase IBM1 in Arabidopsis causes autoimmunity and reshapes the root microbiome".ISME Journal (2022).
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2022.ISME.J.pdf(2083KB) Restricted Access--
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