中文版 | English
Title

Microwave-Assisted Synthesis of Sulfur Quantum Dots for Detection of Alkaline Phosphatase Activity

Author
Corresponding AuthorYang, Minghui; Zhang, Jianglin; Chen, Xiang
Publication Years
2022-08-01
DOI
Source Title
EISSN
2079-4991
Volume12Issue:16
Abstract
Sulfur quantum dots (SQDs) are a kind of pure elemental quantum dots, which are considered as potential green nanomaterials because they do not contain heavy metal elements and are friendly to biology and environment. In this paper, SQDs with size around 2 nm were synthesized by a microwave-assisted method using sulfur powder as precursor. The SQDs had the highest emission under the excitation of 380 nm and emit blue fluorescence at 470 nm. In addition, the SQDs had good water solubility and stability. Based on the synthesized SQDs, a fluorescence assay for detection of alkaline phosphatase (ALP) was reported. The fluorescence of the SQDs was initially quenched by Cr (VI). In the presence of ALP, ALP-catalyzed hydrolysis of 2-phospho-L-ascorbic acid to generate ascorbic acid. The generated ascorbic acid can reduce Cr (VI) to Cr (III), thus the fluorescence intensity of SQDs was restored. The assay has good sensitivity and selectivity and was applied to the detection of ALP in serum samples. The interesting properties of SQDs can find a wide range of applications in different sensing and imaging areas.
Keywords
URL[Source Record]
Indexed By
Language
English
SUSTech Authorship
Corresponding
Funding Project
National Natural Science Foundation of China[22174163] ; Hunan Provincial Science and Technology Plan Project, China[2019TP1001] ; Project of Intelligent Management Software for Multimodal Medical Big Data for New Generation Information Technology, Ministry of Industry and Information Technology of People's Republic of China[TC210804V]
WOS Research Area
Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics
WOS Subject
Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied
WOS Accession No
WOS:000845335900001
Publisher
Data Source
Web of Science
Citation statistics
Cited Times [WOS]:1
Document TypeJournal Article
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/393994
DepartmentShenzhen People's Hospital
Affiliation
1.Cent South Univ, Coll Chem & Chem Engn, Hunan Prov Key Lab Micro & Nano Mat Interface Sci, Changsha 410083, Peoples R China
2.Cent South Univ, State Key Lab Powder Met, Changsha 410083, Peoples R China
3.Jinan Univ, Dept Dermatol, Shenzhen Peoples Hosp,Southern Univ Sci & Technol, Clin Med Coll 2,Affiliated Hosp 1, Shenzhen 518020, Peoples R China
4.Cent South Univ, Xiangya Hosp, Dept Dermatol, Changsha 410008, Peoples R China
Corresponding Author AffilicationShenzhen People's Hospital
Recommended Citation
GB/T 7714
Ma, Fanghui,Zhou, Qing,Yang, Minghui,et al. Microwave-Assisted Synthesis of Sulfur Quantum Dots for Detection of Alkaline Phosphatase Activity[J]. NANOMATERIALS,2022,12(16).
APA
Ma, Fanghui,Zhou, Qing,Yang, Minghui,Zhang, Jianglin,&Chen, Xiang.(2022).Microwave-Assisted Synthesis of Sulfur Quantum Dots for Detection of Alkaline Phosphatase Activity.NANOMATERIALS,12(16).
MLA
Ma, Fanghui,et al."Microwave-Assisted Synthesis of Sulfur Quantum Dots for Detection of Alkaline Phosphatase Activity".NANOMATERIALS 12.16(2022).
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