Title | Microwave-Assisted Synthesis of Sulfur Quantum Dots for Detection of Alkaline Phosphatase Activity |
Author | |
Corresponding Author | Yang, Minghui; Zhang, Jianglin; Chen, Xiang |
Publication Years | 2022-08-01
|
DOI | |
Source Title | |
EISSN | 2079-4991
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Volume | 12Issue:16 |
Abstract | Sulfur quantum dots (SQDs) are a kind of pure elemental quantum dots, which are considered as potential green nanomaterials because they do not contain heavy metal elements and are friendly to biology and environment. In this paper, SQDs with size around 2 nm were synthesized by a microwave-assisted method using sulfur powder as precursor. The SQDs had the highest emission under the excitation of 380 nm and emit blue fluorescence at 470 nm. In addition, the SQDs had good water solubility and stability. Based on the synthesized SQDs, a fluorescence assay for detection of alkaline phosphatase (ALP) was reported. The fluorescence of the SQDs was initially quenched by Cr (VI). In the presence of ALP, ALP-catalyzed hydrolysis of 2-phospho-L-ascorbic acid to generate ascorbic acid. The generated ascorbic acid can reduce Cr (VI) to Cr (III), thus the fluorescence intensity of SQDs was restored. The assay has good sensitivity and selectivity and was applied to the detection of ALP in serum samples. The interesting properties of SQDs can find a wide range of applications in different sensing and imaging areas. |
Keywords | |
URL | [Source Record] |
Indexed By | |
Language | English
|
SUSTech Authorship | Corresponding
|
Funding Project | National Natural Science Foundation of China[22174163]
; Hunan Provincial Science and Technology Plan Project, China[2019TP1001]
; Project of Intelligent Management Software for Multimodal Medical Big Data for New Generation Information Technology, Ministry of Industry and Information Technology of People's Republic of China[TC210804V]
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WOS Research Area | Chemistry
; Science & Technology - Other Topics
; Materials Science
; Physics
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WOS Subject | Chemistry, Multidisciplinary
; Nanoscience & Nanotechnology
; Materials Science, Multidisciplinary
; Physics, Applied
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WOS Accession No | WOS:000845335900001
|
Publisher | |
Data Source | Web of Science
|
Citation statistics |
Cited Times [WOS]:1
|
Document Type | Journal Article |
Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/393994 |
Department | Shenzhen People's Hospital |
Affiliation | 1.Cent South Univ, Coll Chem & Chem Engn, Hunan Prov Key Lab Micro & Nano Mat Interface Sci, Changsha 410083, Peoples R China 2.Cent South Univ, State Key Lab Powder Met, Changsha 410083, Peoples R China 3.Jinan Univ, Dept Dermatol, Shenzhen Peoples Hosp,Southern Univ Sci & Technol, Clin Med Coll 2,Affiliated Hosp 1, Shenzhen 518020, Peoples R China 4.Cent South Univ, Xiangya Hosp, Dept Dermatol, Changsha 410008, Peoples R China |
Corresponding Author Affilication | Shenzhen People's Hospital |
Recommended Citation GB/T 7714 |
Ma, Fanghui,Zhou, Qing,Yang, Minghui,et al. Microwave-Assisted Synthesis of Sulfur Quantum Dots for Detection of Alkaline Phosphatase Activity[J]. NANOMATERIALS,2022,12(16).
|
APA |
Ma, Fanghui,Zhou, Qing,Yang, Minghui,Zhang, Jianglin,&Chen, Xiang.(2022).Microwave-Assisted Synthesis of Sulfur Quantum Dots for Detection of Alkaline Phosphatase Activity.NANOMATERIALS,12(16).
|
MLA |
Ma, Fanghui,et al."Microwave-Assisted Synthesis of Sulfur Quantum Dots for Detection of Alkaline Phosphatase Activity".NANOMATERIALS 12.16(2022).
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