Title | Extracellular pH sensing by plant cell-surface peptide-receptor complexes |
Author | |
Corresponding Author | Chai,Jijie; Guo,Hongwei |
Publication Years | 2022-09-01
|
DOI | |
Source Title | |
ISSN | 0092-8674
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EISSN | 1097-4172
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Volume | 185Issue:18Pages:3341-3355.e13 |
Abstract | The extracellular pH is a vital regulator of various biological processes in plants. However, how plants perceive extracellular pH remains obscure. Here, we report that plant cell-surface peptide-receptor complexes can function as extracellular pH sensors. We found that pattern-triggered immunity (PTI) dramatically alkalinizes the acidic extracellular pH in root apical meristem (RAM) region, which is essential for root meristem growth factor 1 (RGF1)-mediated RAM growth. The extracellular alkalinization progressively inhibits the acidic-dependent interaction between RGF1 and its receptors (RGFRs) through the pH sensor sulfotyrosine. Conversely, extracellular alkalinization promotes the alkaline-dependent binding of plant elicitor peptides (Peps) to its receptors (PEPRs) through the pH sensor Glu/Asp, thereby promoting immunity. A domain swap between RGFR and PEPR switches the pH dependency of RAM growth. Thus, our results reveal a mechanism of extracellular pH sensing by plant peptide-receptor complexes and provide insights into the extracellular pH-mediated regulation of growth and immunity in the RAM. |
Keywords | |
URL | [Source Record] |
Indexed By | |
Language | English
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Important Publications | NI Journal Papers
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SUSTech Authorship | First
; Corresponding
|
Funding Project | National Key Research and Development Program of China[2018YFA0507101];National Key Research and Development Program of China[2019YFA0903904];National Natural Science Foundation of China[31421001];National Natural Science Foundation of China[31971119];National Natural Science Foundation of China[91940303];
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WOS Research Area | Biochemistry & Molecular Biology
; Cell Biology
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WOS Subject | Biochemistry & Molecular Biology
; Cell Biology
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WOS Accession No | WOS:000858905600002
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Publisher | |
ESI Research Field | MOLECULAR BIOLOGY & GENETICS
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Scopus EID | 2-s2.0-85136542729
|
Data Source | Scopus
|
Citation statistics |
Cited Times [WOS]:18
|
Document Type | Journal Article |
Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/395085 |
Department | SUSTech-Peking University National Institute of Plants and Food 生命科学学院 生命科学学院_生物系 |
Affiliation | 1.Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes,Institute of Plant and Food Science,Department of Biology,Southern University of Science and Technology (SUSTech),Shenzhen,Guangdong,518055,China 2.Max-Planck Institute for Plant Breeding Research,Cologne,50829,Germany 3.Institute of Biochemistry,University of Cologne,Cologne,50923,Germany 4.Innovation Center for Structural Biology,School of Life Sciences,Tsinghua University,Beijing,100084,China 5.SUSTech Academy for Advanced and Interdisciplinary Studies,Southern University of Science and Technology,Shenzhen,Guangdong,518055,China 6.Department of Biotechnology,Graduate School of Agricultural and Life Sciences,The University of Tokyo,Tokyo,1-1-1 Yayoi, Bunkyo-ku,113-8657,Japan 7.Research Laboratory of Biomedical Optics and Molecular Imaging,Institute of Biomedical and Health Engineering,Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences,Shenzhen,Guangdong,518055,China |
First Author Affilication | SUSTech-Peking University National Institute of Plants and Food; Department of Biology; School of Life Sciences |
Corresponding Author Affilication | SUSTech-Peking University National Institute of Plants and Food; Department of Biology; School of Life Sciences |
First Author's First Affilication | SUSTech-Peking University National Institute of Plants and Food; Department of Biology; School of Life Sciences |
Recommended Citation GB/T 7714 |
Liu,Li,Song,Wen,Huang,Shijia,et al. Extracellular pH sensing by plant cell-surface peptide-receptor complexes[J]. CELL,2022,185(18):3341-3355.e13.
|
APA |
Liu,Li.,Song,Wen.,Huang,Shijia.,Jiang,Kai.,Moriwaki,Yoshitaka.,...&Guo,Hongwei.(2022).Extracellular pH sensing by plant cell-surface peptide-receptor complexes.CELL,185(18),3341-3355.e13.
|
MLA |
Liu,Li,et al."Extracellular pH sensing by plant cell-surface peptide-receptor complexes".CELL 185.18(2022):3341-3355.e13.
|
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