Utilizing Gradient Porous Graphene Substrate as the Solid-Contact Layer to Enhance Wearable Electrochemical Sweat Sensor Sensitivity

Yeung，Kan Kan1,2; Li，Jingwei1,3; Huang，Ting1; Hosseini，Imman I.4; Al Mahdi，Rakib5; Alam，Md Masruck1; Sun，Honglin1; Mahshid，Sara4; Yang，Jian6; Ye，Terry Tao7; Gao，Zhaoli1,2

2022

10.1021/acs.nanolett.2c01969

NANO LETTERS   Impact Factor & Quartile

1530-6984

1530-6992

Wearable sweat monitoring represents an attractive opportunity for personalized healthcare and for evaluating sports performance. One of the limitations with such monitoring, however, is water layer formation upon cycling of ion-selective sensors, leading to degraded sensitivity and long-Term instability. Our report is the first to use chemical vapor deposition-grown, three-dimensional, graphene-based, gradient porous electrodes to minimize such water layer formation. The proposed design reduces the ion diffusion path within the polymeric ion-selective membrane and enhances the electroactive surface for highly sensitive, real-Time detection of Na+ ions in human sweat with high selectivity. We obtained a 7-fold enhancement in electroactive surface against 2D electrodes (e.g., carbon, gold), yielding a sensitivity of 65.1 ± 0.25 mV decade-1 (n = 3, RSD = 0.39%), the highest to date for wearable Na+ sweat sensors. The on-body sweat sensing performance is comparable to that of ICP-MS, suggesting its feasibility for health evaluation through sweat.

Chemical vapor deposition Electrochemistry Graphene Ion-selective electrodes Sweat sensing Wearable electronics

SCI ; EI

English

NI Journal Papers

Corresponding

Key-Area Research and Development Program of Guangdong Province[2020B0101030002] ; National Natural Science Foundation of China[62101475] ; Research Grant Council of Hong Kong["24201020","14207421"] ; Research Matching Grant Scheme of Hong Kong Government[8601547] ; Wuyi University-Hongkong-Macao Joint Research Funds[2019WGALH19]

Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics

Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter

WOS:000861279800001

AMER CHEMICAL SOC

20223412622707

Electrochemistry ; Graphene ; Ion selective electrodes ; Ions ; Substrates ; Wearable sensors

Nanotechnology:761 ; Electrochemistry:801.4.1 ; Chemical Plants and Equipment:802.1 ; Chemical Reactions:802.2 ; Chemical Products Generally:804

MATERIALS SCIENCE

2-s2.0-85136254134

Scopus

1.Biomedical Engineering Department,Chinese University of Hong Kong,Hong Kong,New Territories,999077,Hong Kong
2.Shenzhen Research Institute,Chinese Univ. of Hong Kong,Shenzhen,518057,China
3.Department of Chemical and Biological Engineering,Hong Kong University of Science and Technology,Kowloon,Clear Water Bay,999077,Hong Kong
4.Department of Bioengineering,McGill University,Montreal,H3A 0E9,Canada
5.Department of Biomedical Engineering,University of Hong Kong,Pokfulam,999077,Hong Kong
6.Faculty of Intelligent Manufacturing,Wuyi University,Jiangmen,529020,China
7.Department of Electrical and Electronic Engineering,Southern University of Science and Technology,Shenzhen,518055,China

Yeung，Kan Kan,Li，Jingwei,Huang，Ting,et al. Utilizing Gradient Porous Graphene Substrate as the Solid-Contact Layer to Enhance Wearable Electrochemical Sweat Sensor Sensitivity[J]. NANO LETTERS,2022,22:6647-6654.

Yeung，Kan Kan.,Li，Jingwei.,Huang，Ting.,Hosseini，Imman I..,Al Mahdi，Rakib.,...&Gao，Zhaoli.(2022).Utilizing Gradient Porous Graphene Substrate as the Solid-Contact Layer to Enhance Wearable Electrochemical Sweat Sensor Sensitivity.NANO LETTERS,22,6647-6654.

Yeung，Kan Kan,et al."Utilizing Gradient Porous Graphene Substrate as the Solid-Contact Layer to Enhance Wearable Electrochemical Sweat Sensor Sensitivity".NANO LETTERS 22(2022):6647-6654.