中文版 | English
Title

子痫前期患者血清晚期氧化蛋白产物及髓过氧化物酶表达水平及其临床意义

Alternative Title
Expression and clinical significance of serum AOPP and MPO in patients with preeclampsia
Author
Publication Years
2022
Source Title
ISSN
1671-8631
Volume31Issue:5Pages:323-326
Abstract
目的:探讨子痫前期孕妇血清中晚期氧化蛋白产物(AOPP)和髓过氧化物酶(MPO)的表达及其临床意义.方法:选取2018年9月-2020年10月收治的50例子痫前期孕妇,根据病情严重程度分为轻度子痫前期(MPE)组25例和重度子痫前期(SPE)组25例,选取同期产检的孕妇25例为对照组.酶联免疫吸附法(ELISA)检测三组AOPP及MPO表达水平,ROC曲线分析诊断价值.结果:SPE组AOPP和MPO的表达显著高于MPE组(P<0.05),SPE组和MPE组AOPP和MPO的表达均高于对照组,差异均有统计学意义(P<0.05).ROC曲线分析:AOPP及MPO用于诊断子痫前期的曲线下面积(AUC)分别为0.906及0.823,截断值为52.35μmol/L,40.45μg/L时,敏感度为74.00%,72.00%,特异度为96.00%,84.00%;两者联合时AUC为0.950,敏感度为90.00%,特异度为96.00%.结论:AOPP及MPO在子痫前期孕妇中均呈高表达,而且两因子联合应用的价值明显高于单独应用.
Keywords
URL[Source Record]
Language
Chinese
SUSTech Authorship
Others
Funding Project
广东省自然科学基金青年项目 ; 国家自然科学基金
Data Source
WanFang
WanFangID
sxlcyy202205002
Document TypeJournal Article
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/401876
DepartmentShenzhen People's Hospital
Affiliation
1.深圳市人民医院,暨南大学第二临床医学院,南方科技大学第一附属医院,广东深圳 518020
2.南方医科大学南方医院,广东广州 510515
Recommended Citation
GB/T 7714
王硕石,钟梅,廖义鸿. 子痫前期患者血清晚期氧化蛋白产物及髓过氧化物酶表达水平及其临床意义[J]. 临床医药实践,2022,31(5):323-326.
APA
王硕石,钟梅,&廖义鸿.(2022).子痫前期患者血清晚期氧化蛋白产物及髓过氧化物酶表达水平及其临床意义.临床医药实践,31(5),323-326.
MLA
王硕石,et al."子痫前期患者血清晚期氧化蛋白产物及髓过氧化物酶表达水平及其临床意义".临床医药实践 31.5(2022):323-326.
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