中文版 | English
Title

A Case of Secondary Pulmonary Syphilis-The Utility of mNGS in Bronchoalveolar Lavage Fluid: A Case Report

Author
Corresponding AuthorXu, Li
Publication Years
2022
DOI
Source Title
ISSN
1178-6973
Volume15
Abstract
Syphilis is a sexually transmitted infectious disease caused by Treponema pallidum. Here, we report a rare case of secondary pulmonary syphilis, which was diagnosed by metagenomic next-generation sequencing (mNGS) in bronchoalveolar lavage fluid (BALF). Direct pulmonary involvement by T. pallidum was suggested by a positive mNGS result in BALF. One month after treatment with benzathine penicillin G (2.4 million units, three doses), a repeated CT scan showed the radiological resolution. To our knowledge, this is the first reported case of secondary pulmonary syphilis diagnosed by mNGS in BALF.
Keywords
URL[Source Record]
Indexed By
Language
English
SUSTech Authorship
Others
WOS Research Area
Infectious Diseases ; Pharmacology & Pharmacy
WOS Subject
Infectious Diseases ; Pharmacology & Pharmacy
WOS Accession No
WOS:000854912900001
Publisher
Data Source
Web of Science
Citation statistics
Cited Times [WOS]:2
Document TypeJournal Article
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/402351
DepartmentShenzhen People's Hospital
Affiliation
1.Jinan Univ, Shenzhen Peoples Hosp, Shenzhen Inst Resp Dis, Clin Med Coll 2, Guangzhou, Peoples R China
2.Southern Univ Sci & Technol, Affiliated Hosp 1, Shenzhen, Guangdong, Peoples R China
3.Jinan Univ, Shenzhen Peoples Hosp The, Dept Infect Dis, Clin Med Coll 2, Guangzhou, Peoples R China
4.First Peoples Hosp Chongqing Liangjiang New Area, Dept Resp & Crit Care Med, Chongqing, Peoples R China
First Author AffilicationShenzhen People's Hospital
Recommended Citation
GB/T 7714
Yang, Xue,Wu, Weigang,Wang, Yongjie,et al. A Case of Secondary Pulmonary Syphilis-The Utility of mNGS in Bronchoalveolar Lavage Fluid: A Case Report[J]. Infection and Drug Resistance,2022,15.
APA
Yang, Xue,Wu, Weigang,Wang, Yongjie,Wu, Wen,Huang, Xia,&Xu, Li.(2022).A Case of Secondary Pulmonary Syphilis-The Utility of mNGS in Bronchoalveolar Lavage Fluid: A Case Report.Infection and Drug Resistance,15.
MLA
Yang, Xue,et al."A Case of Secondary Pulmonary Syphilis-The Utility of mNGS in Bronchoalveolar Lavage Fluid: A Case Report".Infection and Drug Resistance 15(2022).
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