Association between daily sleep duration and the risk of incident dementia according to the presence or absence of diseases among older Japanese individuals in the New Integrated Suburban Seniority Investigation (NISSIN) project

Ukawa，Shigekazu1; Zhao，Wenjing2; Okabayashi，Satoe3; Kimura，Takashi4; Ando，Masahiko5; Wakai，Kenji6; Tsushita，Kazuyo7; Kawamura，Takashi3; Tamakoshi，Akiko4

2022-12-01

10.1016/j.sleep.2022.08.022

SLEEP MEDICINE   Impact Factor & Quartile

1389-9457

1878-5506

Objective: This study aimed to investigate the association between daily sleep duration and incident dementia among physically and socially independent older people with/without diseases (hypertension, diabetes mellitus, cardiovascular diseases) in a Japanese age-specific cohort. Methods: We carried out a prospective cohort study including 1954 (1006 men and 948 women) Japanese individuals aged 64/65 years. Information on daily sleep duration, medical status, demographics, and lifestyle characteristics was collected by a baseline questionnaire survey and health checkup (2000–2005). Dates of incident dementia were confirmed using the nationally standardized dementia scale proposed by the Ministry of Health, Labor, and Welfare. A competing risk model was used to calculate the hazard ratios (HRs) and 95% confidence intervals (CIs) for incident dementia. We treated censored cases due to death as competing events. Results: During a median of 15.6 years of follow-up, 260 participants reported incident dementia. Compared with participants without diseases and who slept 6–7.9 h/day, those with a shorter daily sleep duration of <6 h/day, presence of disease and shorter, moderate, or longer daily sleep duration ≥8 h/day had an increased risk of incident dementia (HR 1.73; 95% CI 1.04–2.88, HR 1.98; 95% CI 1.14–3.44, HR 1.44; 95% CI 1.03–2.00, and HR 2.09; 95% CI 1.41–3.09, respectively) with a significant interaction between the presence of diseases and sleep duration (p < 0.001). Conclusions: The present findings suggest that habitual sleep duration predicts future risk of dementia.

Dementia Prospective cohort study Secondary prevention Sleep duration

SCI

English

Others

Ministry of Education, Culture, Sports, Science and Technology[JP15390197];Ministry of Education, Culture, Sports, Science and Technology[JP20K02392];Ministry of Education, Culture, Sports, Science and Technology[JP25893003];Ministry of Education, Culture, Sports, Science and Technology[JP2646760];Ministry of Education, Culture, Sports, Science and Technology[JP26520105];

Neurosciences & Neurology

Clinical Neurology

WOS:000864082100012

ELSEVIER

NEUROSCIENCE & BEHAVIOR

2-s2.0-85138116948

Scopus

1.Department of Social Welfare Science and Clinical Psychology,Osaka Metropolitan University Graduate School of Human Life and Ecology,Osaka,Japan
2.School of Public Health and Emergency Management,Southern University of Science and Technology,Shenzhen,China
3.Agency for Health,Safety and Environment,Kyoto University,Kyoto,Japan
4.Department of Public Health,Faculty of Medicine,Hokkaido University,Hokkaido,Japan
5.Center for Advanced Medicine and Clinical Research,Nagoya University Hospital,Aichi,Japan
6.Department of Preventive Medicine,Nagoya University Graduate School of Medicine,Aichi,Japan
7.Kagawa Nutrition University,Saitama,Japan

Ukawa，Shigekazu,Zhao，Wenjing,Okabayashi，Satoe,et al. Association between daily sleep duration and the risk of incident dementia according to the presence or absence of diseases among older Japanese individuals in the New Integrated Suburban Seniority Investigation (NISSIN) project[J]. SLEEP MEDICINE,2022,100:190-195.

Ukawa，Shigekazu.,Zhao，Wenjing.,Okabayashi，Satoe.,Kimura，Takashi.,Ando，Masahiko.,...&Tamakoshi，Akiko.(2022).Association between daily sleep duration and the risk of incident dementia according to the presence or absence of diseases among older Japanese individuals in the New Integrated Suburban Seniority Investigation (NISSIN) project.SLEEP MEDICINE,100,190-195.

Ukawa，Shigekazu,et al."Association between daily sleep duration and the risk of incident dementia according to the presence or absence of diseases among older Japanese individuals in the New Integrated Suburban Seniority Investigation (NISSIN) project".SLEEP MEDICINE 100(2022):190-195.