Design Strategies of Tumor-Targeted Delivery Systems Based on 2D Nanomaterials
|Corresponding Author||Gu，Shuo; Wang，Yanli|
Conventional chemotherapy and radiotherapy are nonselective and nonspecific for cell killing, causing serious side effects and threatening the lives of patients. It is of great significance to develop more accurate tumor-targeting therapeutic strategies. Nanotechnology is in a leading position to provide new treatment options for cancer, and it has great potential for selective targeted therapy and controlled drug release. 2D nanomaterials (2D NMs) have broad application prospects in the field of tumor-targeted delivery systems due to their special structure-based functions and excellent optical, electrical, and thermal properties. This review emphasizes the design strategies of tumor-targeted delivery systems based on 2D NMs from three aspects: passive targeting, active targeting, and tumor-microenvironment targeting, in order to promote the rational application of 2D NMs in clinical practice.
Guangdong Basic and Applied Basic Research Foundation["2021A1515110657","2022A1515010056"] ; Shenzhen Science and Technology Program[RCBS20210609104513023] ; National Natural Science Foundation of China ; Shanghai Biomedical Science and Technology Support Project
|WOS Research Area|
Chemistry ; Science & Technology - Other Topics ; Materials Science
Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
|WOS Accession No|
Cited Times [WOS]:7
|Document Type||Journal Article|
|Department||Shenzhen People's Hospital|
1.School of Pharmaceutical Sciences and The First Affiliated Hospital,Hainan Medical University,Haikou,570228,China
2.The First Affiliated Hospital (Shenzhen People's Hospital),Southern University of Science and Technology,Shenzhen,518055,China
3.Translational Medicine Collaborative Innovation Center,Shenzhen People's Hospital (The First Affiliated Hospital,Southern University of Science and Technology,The Second Clinical Medical College of Jinan University),Shenzhen,Guangdong,518055,China
4.Guangdong Engineering Technology Research Centerof Stem Cell and Cell Therapy,Shenzhen Key Laboratory of Stem Cell Research and Clinical Transformation,Shenzhen Immune Cell Therapy Public Service Platform,Shenzhen,518020,China
5.Tumor Precision Targeting Research Center,School of Environmental and Chemical Engineering,Shanghai University,Shanghai,200444,China
6.Department of Gastroenterology,Changzheng Hospital,Naval Medical University,Shanghai,200003,China
7.3B's Research Group,I3Bs-Research Institute on Biomaterials Biodegradables and Biomimetics,University of Minho,Guimarães,4805-017,Portugal
|First Author Affilication||Shenzhen People's Hospital|
Ding，Lin,Liang，Minli,Li，Chenchen,et al. Design Strategies of Tumor-Targeted Delivery Systems Based on 2D Nanomaterials[J]. Small Methods,2022.
Ding，Lin.,Liang，Minli.,Li，Chenchen.,Ji，Xinting.,Zhang，Junfeng.,...&Wang，Yanli.(2022).Design Strategies of Tumor-Targeted Delivery Systems Based on 2D Nanomaterials.Small Methods.
Ding，Lin,et al."Design Strategies of Tumor-Targeted Delivery Systems Based on 2D Nanomaterials".Small Methods (2022).
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