中文版 | English
Title

TAFRO syndrome: A disease that known is half cured

Author
Corresponding AuthorZhou, Jihao
Publication Years
2022-10-01
DOI
Source Title
ISSN
0278-0232
EISSN
1099-1069
Abstract
Thrombocytopenia, anasarca, fever, reticulin fibrosis/renal failure, and organomegaly (TAFRO) syndrome is rare in clinical practice. It is a systemic inflammatory disease caused by a cytokine storm. Its clinical manifestations include thrombocytopenia, systemic edema, fever, bone marrow fibrosis, renal insufficiency, and organ enlargement. The high mortality rate of TAFRO syndrome is due to the difficulty of acquiring biopsy samples for diagnosis and the rapid disease progression. This disease is poorly understood by clinicians. Early detection, accurate diagnosis, and timely treatment play key roles in prolonging the survival of the patients. This review summarizes the latest progress in the pathogenesis, diagnostic criteria, and treatment regimens of TAFRO syndrome, aiming to help clinicians better understand TAFRO syndrome and improve its diagnosis and treatment.
Keywords
URL[Source Record]
Indexed By
Language
English
SUSTech Authorship
Corresponding
Funding Project
Sanming Project of Medicine in Shenzhen[SZSM201512006] ; National Natural Science Foundation of China["81600168","81702082"]
WOS Research Area
Oncology ; Hematology
WOS Subject
Oncology ; Hematology
WOS Accession No
WOS:000862997100001
Publisher
ESI Research Field
CLINICAL MEDICINE
Data Source
Web of Science
Citation statistics
Cited Times [WOS]:1
Document TypeJournal Article
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/406024
DepartmentShenzhen People's Hospital
Affiliation
1.Jinan Univ, Clin Med Coll 2, Dept Hematol, Shenzhen, Guangdong, Peoples R China
2.Shenzhen Peoples Hosp, Dept Hematol, 1017 Dongmen North Rd, Shenzhen 518000, Guangdong, Peoples R China
3.Southern Univ Sci & Technol, Affiliated Hosp 1, Shenzhen, Guangdong, Peoples R China
Corresponding Author AffilicationShenzhen People's Hospital
Recommended Citation
GB/T 7714
Chen, Tingting,Feng, Chun,Zhang, Xinyou,et al. TAFRO syndrome: A disease that known is half cured[J]. HEMATOLOGICAL ONCOLOGY,2022.
APA
Chen, Tingting,Feng, Chun,Zhang, Xinyou,&Zhou, Jihao.(2022).TAFRO syndrome: A disease that known is half cured.HEMATOLOGICAL ONCOLOGY.
MLA
Chen, Tingting,et al."TAFRO syndrome: A disease that known is half cured".HEMATOLOGICAL ONCOLOGY (2022).
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