| Title | beta-C-Glycosylation with 2-Oxindole Acceptors via Palladium- Reactions |
| Author | |
| Corresponding Author | Lu, Zhiqiang; Xiang, Shao-Hua |
| Publication Years | 2022-09-01
|
| DOI | |
| Source Title | |
| ISSN | 1523-7060
|
| EISSN | 1523-7052
|
| Abstract | This report describes a highly efficient beta-selective C-glycosylation of bicyclic galactals with 2-oxindoles through a palladium-catalyzed decarboxylative pathway. A variety of sub-strates representing both glycosyl donors and acceptors could be transformed in greater than 90% yields under mild reaction conditions. The decarboxylation intermediate of galactal could serve as an efficient base to deprotonate the enol tautomer of 2-oxindole and enhance its nucleophilicity. The beta-selective nucleophilic addition at the anomeric center originates from the steric hindrance imposed by the palladium and bulky ligand. |
| URL | [Source Record] |
| Indexed By | |
| Language | English
|
| Important Publications | NI Journal Papers
|
| SUSTech Authorship | First
; Corresponding
|
| Funding Project | Shenzhen Special Funds[JCYJ20180305123508258]
|
| WOS Research Area | Chemistry
|
| WOS Subject | Chemistry, Organic
|
| WOS Accession No | WOS:000861273400001
|
| Publisher | |
| ESI Research Field | CHEMISTRY
|
| Data Source | Web of Science
|
| Citation statistics |
Cited Times [WOS]:1
|
| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/406067 |
| Department | Department of Chemistry |
| Affiliation | 1.Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Peoples R China 2.Luoyang Normal Univ, Coll Chem & Chem Engn, Henan Key Lab Funct Oriented Porous Mat, Luoyang 471934, Peoples R China |
| First Author Affilication | Department of Chemistry |
| Corresponding Author Affilication | Department of Chemistry |
| First Author's First Affilication | Department of Chemistry |
| Recommended Citation GB/T 7714 |
Ding, Wei-Yi,Zhao, Hao-Wen,Cheng, Jun Kee,et al. beta-C-Glycosylation with 2-Oxindole Acceptors via Palladium- Reactions[J]. ORGANIC LETTERS,2022.
|
| APA |
Ding, Wei-Yi,Zhao, Hao-Wen,Cheng, Jun Kee,Lu, Zhiqiang,Xiang, Shao-Hua,&Tan, Bin.(2022).beta-C-Glycosylation with 2-Oxindole Acceptors via Palladium- Reactions.ORGANIC LETTERS.
|
| MLA |
Ding, Wei-Yi,et al."beta-C-Glycosylation with 2-Oxindole Acceptors via Palladium- Reactions".ORGANIC LETTERS (2022).
|
| Files in This Item: | There are no files associated with this item. | |||||
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