| Title | Clinicopathological characteristics, survival outcomes and prognostic factors in the cT1N0M0 pancreatic neuroendocrine tumors: A SEER-based study |
| Author | |
| Corresponding Author | Liang, Zhen |
| Publication Years | 2022-10-14
|
| DOI | |
| Source Title | |
| ISSN | 0025-7974
|
| EISSN | 1536-5964
|
| Volume | 101Issue:41 |
| Abstract | Small nonfunctional pancreatic neuroendocrine tumors <= 2 cm have different biological features, and there is no gold standard treatment for them. This study aimed to assess the risk of malignancy of small non-functional pancreatic neuroendocrine tumors and their outcomes after radical resection. The optimal management of small, incidentally detected pancreatic neuroendocrine tumors is controversial, with the aim of identifying factors predicting survival in patients with clinical stage T1N0M0 (cT1N0M0) pancreatic neuroendocrine tumors and whether surgical treatment improves survival. Using the Surveillance, Epidemiology, and End Results database, we identified 637 patients with cT1N0M0 pancreatic neuroendocrine tumors from 2010 to 2015, including clinicopathological characteristics, treatment modalities, and outcome data. From the surveillance, epidemiology, and end results database of 637 patients with cT1N0M0 PNENs, 564 were treated surgically. Age (P = .000), sex (P < .001), and surgery (P < .001) were independent risk factors affecting survival. Patients who have undergone surgery, women and young adults have a higher overall survival rate. The following independent prognostic predictors for cT1N0M0 pNENs were identified: age, sex, and surgery. At last, we concluded that Surgery can increase the overall survival of pancreatic neuroendocrine tumors in T1N0M0. |
| Keywords | |
| URL | [Source Record] |
| Indexed By | |
| Language | English
|
| SUSTech Authorship | Corresponding
|
| Funding Project | Natural Science Foundation of Shenzhen City, China[KCXFZ20201221173600001]
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| WOS Research Area | General & Internal Medicine
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| WOS Subject | Medicine, General & Internal
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| WOS Accession No | WOS:000868085500004
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| Publisher | |
| ESI Research Field | CLINICAL MEDICINE
|
| Data Source | Web of Science
|
| Citation statistics |
Cited Times [WOS]:2
|
| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/406506 |
| Department | Shenzhen People's Hospital |
| Affiliation | 1.Jinan Univ Guangdong, Dept Endocrinol, Clin Sch Med 2, Guangzhou, Guangdong, Peoples R China 2.Jinan Univ, Dept Geriatr, Shenzhen Peoples Hosp, Clin Med Coll 2, 1017 Dongmen North Rd, Shenzhen 518000, Guangdong, Peoples R China 3.Southern Univ Sci & Technol, Affiliated Hosp 1, 1017 Dongmen North Rd, Shenzhen 518000, Guangdong, Peoples R China 4.Jinan Univ Guangdong, Clin Sch Med 2, Dept Geriatr, Guangzhou, Guangdong, Peoples R China |
| Corresponding Author Affilication | Shenzhen People's Hospital |
| Recommended Citation GB/T 7714 |
Guo, Nian,Liang, Zhen,Xiong, Li Jiao. Clinicopathological characteristics, survival outcomes and prognostic factors in the cT1N0M0 pancreatic neuroendocrine tumors: A SEER-based study[J]. MEDICINE,2022,101(41).
|
| APA |
Guo, Nian,Liang, Zhen,&Xiong, Li Jiao.(2022).Clinicopathological characteristics, survival outcomes and prognostic factors in the cT1N0M0 pancreatic neuroendocrine tumors: A SEER-based study.MEDICINE,101(41).
|
| MLA |
Guo, Nian,et al."Clinicopathological characteristics, survival outcomes and prognostic factors in the cT1N0M0 pancreatic neuroendocrine tumors: A SEER-based study".MEDICINE 101.41(2022).
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