Combined application of moist exposed burn ointment and maggot therapy in wound healing

Song，Mingzhi1,2; Bai，Xiaodong3; Wang，Deyu4; Wang，Qingxin5; Pan，Liwen6,7; He，Ping6,7; Gong，Ying1,6; Sun，Xiaohong6; Xu，Xiaoguang8,9; Che，Jianzhong4; Wang，Shouyu1,10

2022-10-01

10.12968/jowc.2022.31.Sup10.S41

Journal of Wound Care   Impact Factor & Quartile

0969-0700

2062-2916

OBJECTIVE: Hard-to-heal wounds are a global health challenge, and effective treatments are still lacking. Moist exposed burn ointment (MEBO) and maggots are traditional treatments for promoting wound healing. This study was a preliminary exploration of combined maggot therapy and MEBO in the treatment of hard-to-heal wounds. METHOD: A coexistence experiment was conducted to determine the survival rates of maggots in MEBO. The maggots were placed in two different existence conditions: one set in MEBO (MEBO group), and another set as the control group (no MEBO) to compare survival rates. Case reports describe the use of the combined application of MEBO and maggots in the treatment of patients with hard-to-heal wounds. RESULTS: The coexistence experiment indicated that maggots in the MEBO group had a higher survival rate. From the therapeutic effect of the clinical cases (n=7), the combined application was safe and effective, with all the reported wounds eventually healing. CONCLUSION: Based on the findings of this study, we believe the combined application of MEBO and maggots is a promising way of promoting wound healing. Further studies and clinical trials are needed to elucidate the mechanism of the combined application in promoting wound healing and to more persuasively clarify the therapeutic effect.

chronic hard-to-heal maggot therapy maggots MEBO moist exposed burn ointment wound wound care wound dressing wound healing

SCI

English

Others

Natural Science Foundation of China["82074426","81573734","82204822"] ; Liaoning Revitalization Talents Program[XLYC1802014] ; Liaoning Key Research and Development Planning Project[2017226015] ; Dalian Outstanding Youth Science And Technology Talent Project[2015R003]

Dermatology

Dermatology

WOS:000871258600005

MA HEALTHCARE LTD

2-s2.0-85139888549

Scopus

1.Department of Orthopaedics,First Affiliated Hospital of Dalian Medical University,Dalian,China
2.Department of Orthopaedics,Third Affiliated Hospital of Dalian Medical University,Dalian,China
3.Department of Plastic Surgery,Southern University of Science and Technology Hospital,Shenzhen,China
4.Department of Burn and Wound Repair Surgery,Forth People's Hospital of Dalian,Dalian,China
5.The Second Department of General Surgery,Fifth People's Hospital of Dalian,Dalian,China
6.Department of Nursing,First Affiliated Hospital of Dalian Medical University,Dalian,China
7.Surgical Clinic,First Affiliated Hospital of Dalian Medical University,Dalian,China
8.Research Center of High Altitude Medicine,China
9.People's Hospital of Naqu Affiliated to Dalian Medical University,China
10.10 Dalian Runxi Technology Development Co. Ltd,Dalian,China

Song，Mingzhi,Bai，Xiaodong,Wang，Deyu,et al. Combined application of moist exposed burn ointment and maggot therapy in wound healing[J]. Journal of Wound Care,2022,31(10):S41-S52.

Song，Mingzhi.,Bai，Xiaodong.,Wang，Deyu.,Wang，Qingxin.,Pan，Liwen.,...&Wang，Shouyu.(2022).Combined application of moist exposed burn ointment and maggot therapy in wound healing.Journal of Wound Care,31(10),S41-S52.

Song，Mingzhi,et al."Combined application of moist exposed burn ointment and maggot therapy in wound healing".Journal of Wound Care 31.10(2022):S41-S52.