Self-organized canals enable long range directed material transport in bacterial communities
|Corresponding Author||Yang，Liang; Wu，Yilin|
Long-range material transport is essential to maintain the physiological functions of multicellular organisms such as animals and plants. By contrast, material transport in bacteria is often short-ranged and limited by diffusion. Here we report a unique form of actively regulated long-range directed material transport in structured bacterial communities. Using Pseudomonas aeruginosa colonies as a model system, we discover that a large-scale and temporally evolving open channel system spontaneously develops in the colony via shear-induced banding. Fluid flows in the open channels support high-speed (up to 450 µm/s) transport of cells and outer membrane vesicles over centimeters, and help to eradicate colonies of a competing species Staphylococcus aureus. The open channels are reminiscent of human-made canals for cargo transport, and the channel flows are driven by interfacial tension mediated by cell-secreted biosurfactants. The spatial-temporal dynamics of fluid flows in the open channels are qualitatively described by flow profile measurement and mathematical modeling. Our findings demonstrate that mechanochemical coupling between interfacial force and biosurfactant kinetics can coordinate large-scale material transport in primitive life forms, suggesting a new principle to engineer self-organized microbial communities.
NI Journal Papers
Natural Science Foundation of Guangdong Province[2020B1515020003];
|WOS Research Area|
Life Sciences & Biomedicine - Other Topics
|WOS Accession No|
Cited Times [WOS]:1
|Document Type||Journal Article|
|Department||School of Medicine|
1.Department of Physics and Shenzhen Research Institute,The Chinese University of Hong Kong,Shatin, NT,Hong Kong
2.School of Medicine,Southern University of Science and Technology,Shenzhen,China
3.Singapore Center for Environmental Life Science Engineering,Nanyang Technological University,Singapore
|Corresponding Author Affilication||School of Medicine|
Li，Ye,Liu，Shiqi,Zhang，Yingdan,et al. Self-organized canals enable long range directed material transport in bacterial communities[J]. eLife,2022,11.
Li，Ye.,Liu，Shiqi.,Zhang，Yingdan.,Seng，Zi Jing.,Xu，Haoran.,...&Wu，Yilin.(2022).Self-organized canals enable long range directed material transport in bacterial communities.eLife,11.
Li，Ye,et al."Self-organized canals enable long range directed material transport in bacterial communities".eLife 11(2022).
|Files in This Item:||There are no files associated with this item.|
|Recommend this item|
|Export to Endnote|
|Export to Excel|
|Export to Csv|
|Similar articles in Google Scholar|
|Similar articles in Baidu Scholar|
|Similar articles in Bing Scholar|
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.