Photodynamic viral inactivation assisted by photosensitizers
|Corresponding Author||Biazar，E.; Jin，D.|
The deadly viruses, which are spreading worldwide at an alarming rate, are a major challenge for the life sciences. More efficient and cost-effective methods with fewer side effects can provide a good alternative to traditional drug-based methods. Currently, physical phenomena such as light in the form of photodynamic action are increasingly being used to inactivate viruses. Photodynamic inactivation (PDI) uses a photosensitizer (PS), light, and oxygen to generate reactive oxygen species (ROS) to inactivate microorganisms. This article reviews the use of existing PSs, as one of the essential anti-viral agents, and introduces new materials and strategies combined with PDI. Physiochemical properties of PSs and their role in interaction with virus components are discussed. Furthermore, the effectiveness of optical sensitizers with radiation methods to inactivate viruses is highlighted.
Australia China Science and Research Fund Joint Research Center for Point-of-Care Testing["ACSRF658277","SQ2017YFGH001190"] ; Science and Technology Inno-vation Commission of Shenzhen[KQTD20170810110913065] ; Australian Research Council Laureate Fellowship Program[FL210100180]
|WOS Research Area|
Materials Science ; Physics
Materials Science, Multidisciplinary ; Physics, Applied
|WOS Accession No|
Cited Times [WOS]:2
|Document Type||Journal Article|
|Department||Department of Biomedical Engineering|
1.Institute for Biomedical Materials and Devices (IBMD),Faculty of Science,University of Technology Sydney,Sydney,2007,Australia
2.Department of Oral and Maxillofacial Surgery,Division of Regenerative Orofacial Medicine,University Hospital Hamburg-Eppendorf,Hamburg,20251,Germany
3.Department of Biomedical Engineering,Islamic Azad University,Tonekabon,Tonekabon Branch,Iran
4.UTS-SUStech Joint Research Centre for Biomedical Materials & Devices,Department of Biomedical Engineering,College of Engineering,Southern University of Science and Technology,Shenzhen,Guangdong,China
|Corresponding Author Affilication||Department of Biomedical Engineering; College of Engineering|
Sadraeian，M.,Zhang，Le,Aavani，F.,et al. Photodynamic viral inactivation assisted by photosensitizers[J]. Materials Today Physics,2022,28.
Sadraeian，M.,Zhang，Le,Aavani，F.,Biazar，E.,&Jin，D..(2022).Photodynamic viral inactivation assisted by photosensitizers.Materials Today Physics,28.
Sadraeian，M.,et al."Photodynamic viral inactivation assisted by photosensitizers".Materials Today Physics 28(2022).
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