Title | Recent advances on bioactive baghdadite ceramic for bone tissue engineering applications: 20 years of research and innovation (a review) |
Author | |
Corresponding Author | Sadeghzade,Sorour; Yuan,Hongyan |
Publication Years | 2022-10-25
|
DOI | |
Source Title | |
ISSN | 2590-0064
|
EISSN | 2590-0064
|
Volume | 17 |
Abstract | Various artificial bone graft substitutes based on ceramics have been developed over the last 20 years. Among them, calcium-silicate-based ceramics, which are osteoconductive and can attach directly to biological organs, have received great attention for bone tissue engineering applications. However, the degradation rate of calcium-silicate and bone formation is often out of balance, resulting in stress shielding (osteopenia). A new strategy to improve the drawbacks of these ceramics is incorporating trace elements such as Zn, Mg, and Zr into their lattice structures, enhancing their physical and biological properties. Recently, baghdadite (CaZrSiO) ceramic, one of the most appealing calcium-silicate-based ceramics, has demonstrated high bioactivity, biocompatibility, biodegradability, and cell interaction. Because of its physical, mechanical, and biological properties and ability to be shaped using various fabrication techniques, baghdadite has found high potential in various biomedical applications such as coatings, fillers, cement, scaffolds, and drug delivery systems. Undoubtedly, there is a high potential for this newly developed ceramic to contribute significantly to therapies to provide a tremendous clinical outcome. This review paper aims to summarize and discuss the most relevant studies performed on baghdadite-based ceramics and composites by focusing on their behavior in vivo and in vitro. |
Keywords | |
URL | [Source Record] |
Indexed By | |
Language | English
|
SUSTech Authorship | First
; Corresponding
|
Funding Project | Science, Technology and Innovation Commission of Shenzhen Municipality[ZDSYS20210623092005017]
|
WOS Research Area | Engineering
; Materials Science
|
WOS Subject | Engineering, Biomedical
; Materials Science, Biomaterials
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WOS Accession No | WOS:000883714400002
|
Publisher | |
Scopus EID | 2-s2.0-85140878826
|
Data Source | Scopus
|
Citation statistics |
Cited Times [WOS]:11
|
Document Type | Journal Article |
Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/407083 |
Department | Department of Mechanics and Aerospace Engineering 南方科技大学医学院 工学院_生物医学工程系 南方科技大学医学院_生物化学系 |
Affiliation | 1.Shenzhen Key Laboratory of Soft Mechanics & Smart Manufacturing,Department of Mechanics and Aerospace Engineering,Southern University of Science and Technology,Shenzhen,518055,China 2.Department of Biochemistry,School of Medicine,Southern University of Science and Technology,Shenzhen,518055,China 3.Department of Biomedical Engineering,Southern University of Science and Technology,Shenzhen,518055,China |
First Author Affilication | Department of Mechanics and Aerospace Engineering |
Corresponding Author Affilication | Department of Mechanics and Aerospace Engineering |
First Author's First Affilication | Department of Mechanics and Aerospace Engineering |
Recommended Citation GB/T 7714 |
Sadeghzade,Sorour,Liu,Jingyi,Wang,Huiru,et al. Recent advances on bioactive baghdadite ceramic for bone tissue engineering applications: 20 years of research and innovation (a review)[J]. Materials Today Bio,2022,17.
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APA |
Sadeghzade,Sorour.,Liu,Jingyi.,Wang,Huiru.,Li,Xin.,Cao,Jinrui.,...&Yuan,Hongyan.(2022).Recent advances on bioactive baghdadite ceramic for bone tissue engineering applications: 20 years of research and innovation (a review).Materials Today Bio,17.
|
MLA |
Sadeghzade,Sorour,et al."Recent advances on bioactive baghdadite ceramic for bone tissue engineering applications: 20 years of research and innovation (a review)".Materials Today Bio 17(2022).
|
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