Association of decreases in PM2.5 levels due to the implementation of environmental protection policies with the incidence of obesity in adolescents: A prospective cohort study
Aims: To explore the association between decreased levels of particulate matter (≤2.5 µm; PM) due to the implementation of environmental protection policies and the incidence of obesity in adolescents in Chongqing, China through a prospective cohort study. Methods: A total of 2105 children (52.02% male; aged 7.33 ± 0.60 years at baseline) were enrolled from the Chongqing Children's Health Cohort. A mixed linear regression model was used to analyse the relationships of PM levels with obesity indicators after adjusting for covariates. Additionally, a Poisson regression model was used to determine the relationship between PM exposure and the incidence of overweight/obesity. Results: The average PM exposure levels from participant conception to 2014, from 2015 to 2017, and from 2018 to 2019 were 66.64 ± 5.33 μg/m, 55.49 ± 3.78 μg/m, and 42.50 ± 1.87 μg/m, respectively; these levels significantly decreased over time (P < 0.001). Throughout the entire follow-up period, the incidence of overweight/obesity after a ≥ 25 μg/m decrease in the PM level was 4.57% among females; this incidence was the lowest among females who experienced remarkable decreases in PM exposure. A 1-µg/m decrease in the PM level significantly decreased the body mass index (BMI), BMI z score (BMI), and weight of adolescents (all P < 0.001). Compared with a < 20-μg/m decrease in the PM level, a ≥ 25-μg/m decrease protected against increased BMI (net difference= −0.93; 95% confidence interval [CI]: (−1.23,−0.63) kg/m), BMI (−0.28 (−0.39, −0.17)), weight (−1.59 (−2.44, −0.74) kg), and incidence of overweight/obesity (0.48 (0.37, 0.62), P < 0.001). Moreover, compared with a < 20-μg/m decrease in the PM level, a ≥ 25-μg/m decrease resulted in significant absolute differences in BMI (−1.26 (−1.56, −0.96) kg/m), BMI (−0.53 (−0.65, −0.40)) and weight (−3.01 (−3.8, −2.19) kg) (all P < 0.001). Conclusions: This study showed the etiological relevance of declining PM concentrations for the incidence of obesity in children and adolescents, suggesting that controlling ambient air pollutants may prevent the development of obesity in this age group. Continuous implementation of environmental protection policies in China has led to substantial health benefits.
Chongqing Municipal Education Commission[KJQN201900443] ; Chongqing Medical University[W0088]
|WOS Research Area|
Environmental Sciences & Ecology ; Toxicology
Environmental Sciences ; Toxicology
|WOS Accession No|
|ESI Research Field|
Cited Times [WOS]:1
|Document Type||Journal Article|
|Department||School of Public Health and Emergency Management|
1.Department of Clinical Epidemiology and Biostatistics,Children's Hospital of Chongqing Medical University,National Clinical Research Center for Child Health and Disorders,Ministry of Education Key Laboratory of Child Development and Disorders,Chongqing Key Laboratory of Pediatrics,Chongqing,400016,China
2.Department of Epidemiology,Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,100037,China
3.School of Public Health and Emergency Management,Southern University of Science and Technology,Shenzhen,518055,China
Liang，Xiaohua,Liu，Fangchao,Liang，Fengchao,et al. Association of decreases in PM2.5 levels due to the implementation of environmental protection policies with the incidence of obesity in adolescents: A prospective cohort study[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2022,247.
Liang，Xiaohua.,Liu，Fangchao.,Liang，Fengchao.,Ren，Yanling.,Tang，Xian.,...&Feng，Wei.(2022).Association of decreases in PM2.5 levels due to the implementation of environmental protection policies with the incidence of obesity in adolescents: A prospective cohort study.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,247.
Liang，Xiaohua,et al."Association of decreases in PM2.5 levels due to the implementation of environmental protection policies with the incidence of obesity in adolescents: A prospective cohort study".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 247(2022).
|Files in This Item:|
|Association of decre（3187KB）||Open Access||--||View|
|Recommend this item|
|Export to Endnote|
|Export to Excel|
|Export to Csv|
|Similar articles in Google Scholar|
|Similar articles in Baidu Scholar|
|Similar articles in Bing Scholar|
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.