Cancer Diagnosis Using Terahertz-Graphene-Metasurface-Based Biosensor with Dual-Resonance Response

Tan，Chunjian1,2; Wang，Shaogang1,2; Li，Shizhen2; Liu，Xu1,2; Wei，Jia3; Zhang，Guoqi1; Ye，Huaiyu2

2022-11-01

10.3390/nano12213889

Nanomaterials   Impact Factor & Quartile

2079-4991

Owing to the outstanding physical properties of graphene, its biosensing applications implemented by the terahertz metasurface are widely concerned and studied. Here, we present a novel design of the graphene metasurface, which consists of an individual graphene ring and an H-shaped graphene structure. The graphene metasurface exhibits a dual-resonance response, whose resonance frequency strongly varies with the geometrical parameters of the proposed metasurface, the carrier density of graphene, and the analyte composition. The transparency window, including width and position, can be artificially controlled by adjusting the geometrical parameters or the Fermi energy. Furthermore, the sensing parameters of the graphene metasurface for cancerous and normal cells are investigated, focusing on two factors, namely cell quantity and position on the metasurface. The simulated results clearly show that the theoretical sensitivity, figure of merit, and quantity of the graphene metasurface for breast cells reach 1.21 THz/RIU, 2.75 RIU (Formula presented.), and 2.43, respectively. Our findings may open up new avenues for promising applications in the diagnosis of cancers.

cancer diagnosis dual-resonance response graphene metasurface terahertz sensing

SCI

English

Corresponding

Shenzhen Fundamental Research Program[JCYJ20200109140822796];

Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics

Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied

WOS:000883558200001

MDPI

2-s2.0-85141872891

Scopus

1.Electronic Components,Technology and Materials,Delft University of Technology,Delft,2628 CD,Netherlands
2.Engineering Research Center of Integrated Circuits for Next-Generation Communications,Ministry of Education,School of Microelectronics,Southern University of Science and Technology,Shenzhen,518055,China
3.Bioland Laboratory,Guangzhou Regenerative Medicine and Health Guangdong Laboratory,Guangzhou,510005,China

Tan，Chunjian,Wang，Shaogang,Li，Shizhen,et al. Cancer Diagnosis Using Terahertz-Graphene-Metasurface-Based Biosensor with Dual-Resonance Response[J]. Nanomaterials,2022,12(21).

Tan，Chunjian.,Wang，Shaogang.,Li，Shizhen.,Liu，Xu.,Wei，Jia.,...&Ye，Huaiyu.(2022).Cancer Diagnosis Using Terahertz-Graphene-Metasurface-Based Biosensor with Dual-Resonance Response.Nanomaterials,12(21).

Tan，Chunjian,et al."Cancer Diagnosis Using Terahertz-Graphene-Metasurface-Based Biosensor with Dual-Resonance Response".Nanomaterials 12.21(2022).