Large Area Patterning of Highly Reproducible and Sensitive SERS Sensors Based on 10-nm Annular Gap Arrays

Luo，Sihai1; Mancini，Andrea2; Lian，Enkui1; Xu，Wenqi3; Berté，Rodrigo2; Li，Yi2,4

2022-11-01

10.3390/nano12213842

Nanomaterials   Impact Factor & Quartile

2079-4991

Applicable surface-enhanced Raman scattering (SERS) active substrates typically require low-cost patterning methodology, high reproducibility, and a high enhancement factor (EF) over a large area. However, the lack of reproducible, reliable fabrication for large area SERS substrates in a low-cost manner remains a challenge. Here, a patterning method based on nanosphere lithography and adhesion lithography is reported that allows massively parallel fabrication of 10-nm annular gap arrays on large areas. The arrays exhibit excellent reproducibility and high SERS performance, with an EF of up to 10. An effective wearable SERS contact lens for glucose detection is further demonstrated. The technique described here extends the range of SERS-active substrates that can be fabricated over large areas, and holds exciting potential for SERS-based chemical and biomedical detection.

adhesion lithography glucose nanogaps nanospheres lithography sensors surface-enhanced Raman spectroscopy

SCI

English

Others

Norges Forskningsråd[221860/F60];National Taiwan Normal University[81771118];Norges Teknisk-Naturvitenskapelige Universitet[81771118];

Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics

Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied

WOS:000881424800001

MDPI

2-s2.0-85141833008

Scopus

1.Department of Chemistry,Norwegian University of Science and Technology (NTNU),Trondheim,7491,Norway
2.Nanoinstitute Munich,Faculty of Physics,Ludwig-Maximilians-Universität München,München,Königinstrasse 10,80539,Germany
3.Department of Chemical Engineering,Norwegian University of Science and Technology (NTNU),Trondheim,7491,Norway
4.School of Microelectronics,MOE Engineering Research Center of Integrated Circuits for Next Generation Communications,Southern University of Science and Technology,Shenzhen,518055,China

Luo，Sihai,Mancini，Andrea,Lian，Enkui,et al. Large Area Patterning of Highly Reproducible and Sensitive SERS Sensors Based on 10-nm Annular Gap Arrays[J]. Nanomaterials,2022,12(21).

Luo，Sihai,Mancini，Andrea,Lian，Enkui,Xu，Wenqi,Berté，Rodrigo,&Li，Yi.(2022).Large Area Patterning of Highly Reproducible and Sensitive SERS Sensors Based on 10-nm Annular Gap Arrays.Nanomaterials,12(21).

Luo，Sihai,et al."Large Area Patterning of Highly Reproducible and Sensitive SERS Sensors Based on 10-nm Annular Gap Arrays".Nanomaterials 12.21(2022).