| Title | Research progress on pharmacological effect of evodiamine ? 茱 ? 碱的 ? ? 学研究进 |
| Author | |
| Publication Years | 2022
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| DOI | |
| Source Title | |
| ISSN | 1001-1978
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| Volume | 38Issue:10Pages:1457-1461 |
| Abstract | Evodiamine(EVO)is an indoloquinazoline alkaloid isolated from the fruits of Euodia rutaecarpa,which has long been used in traditional Chinese medicine to treat various diseases.Modern medical research shows that evodiamine has various pharmacological activities and extremely high medicinal value such as anti-inflammation,anti-tumor,losing weight,treating Alzheimer's,and antibacterium.Evodiamine can interact with a variety of proteins.For example,the interaction between evodiamine and TRPV1 induces its activation to exert anti-inflammatory and losing weight; the interaction with DNA topoisomerase I inhibits its function and thus inhibit bacterial proliferation; the interaction with tubulin promotes NLRP3 inflammasome activation,and exerts anti-tumor and anti-inflammatory functions.In recent years,with the in-depth study of evodiamine,pharmacological research and mechanism of evodiamine has significant improvement.Recent progress of pharmacological effect of evodiamine is highlighted in this review. |
| Keywords | |
| URL | [Source Record] |
| Language | Chinese
|
| SUSTech Authorship | Others
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| Scopus EID | 2-s2.0-85141832252
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| Data Source | Scopus
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| Citation statistics |
Cited Times [WOS]:0
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| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/411863 |
| Department | Southern University of Science and Technology |
| Affiliation | 1.Shenzhen University Health Science Center,School of Biomedical Engineering,Shenzhen,518060,China 2.Huazhong University of Science and Technology Union Shenzhen Hospital,Pain Management,Shenzhen,518052,China 3.Southern University of Science and Technology,Dept of Medicine,Shenzhen,518055,China |
| Recommended Citation GB/T 7714 |
Liang，Jing Rong,Mai，Feng Yi,Li，Chen Guang,等. Research progress on pharmacological effect of evodiamine ? 茱 ? 碱的 ? ? 学研究进[J]. 中国药理学通报,2022,38(10):1457-1461.
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| APA |
Liang，Jing Rong,Mai，Feng Yi,Li，Chen Guang,Liao，Xiang,&Zhang，Zhi Guo.(2022).Research progress on pharmacological effect of evodiamine ? 茱 ? 碱的 ? ? 学研究进.中国药理学通报,38(10),1457-1461.
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| MLA |
Liang，Jing Rong,et al."Research progress on pharmacological effect of evodiamine ? 茱 ? 碱的 ? ? 学研究进".中国药理学通报 38.10(2022):1457-1461.
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