An Artificial Thermal Nociceptor Based on Xanthan Gum-Gated Synaptic Transistors to Emulate Human Thermal Nociception

Li, Fang Zhou1; Liu, Hong Rui1; Guo, Jian Miao1; Zhou, Xin Yi1; Liu, Ke Kang1; Liang, Lin Zi1; Pei, Xin Yi1; Zhou, Fei Chi2; Huang, Feng1; Wang, Hong1; Liu, Yang Hui1

2022-10-01

10.1002/aisy.202200233

ADVANCED INTELLIGENT SYSTEMS   Impact Factor & Quartile

2640-4567

Nociceptors are kinds of sensory neurons that send warning information to the central nervous system in response to noxious stimuli. Thermal nociception happens as the thermal stimulus exceeds 45 degrees C as this temperature is perceived to be potentially harmful. Simulating this function is of great significance to developing bioinspired electronic skins and humanoid robots, which thus creates more demands for electronic devices that can simulate thermal nociception. Herein, an artificial thermal nociceptor (ATN) is fabricated by integrating a temperature sensor and a synaptic transistor, which can simulate the thermal pain threshold of the human body and operates in a very similar way as the transient receptor potential vanilloid 1 (TRPV1). For this ATN, the function of temperature sensing is realized by a graphite-polydimethylsiloxane (Gr-PDMS) composite temperature sensor, and the synaptic functions, as well as nociceptor features, are emulated through a synaptic transistor using xanthan gum polysaccharide electrolyte as gate dielectric, providing energy-efficient building blocks for brain-inspired computation systems. In a word, the ATN proposed can help to open a new avenue and provides more possibilities in the design of artificial sensory systems with the functions of temperature perception and thermal feedback.

artificial thermal nociceptors human thermal threshold synaptic transistors transient receptor potential vanilloid 1 (TRPV1) xanthan gum electrolyte

SCI

English

Others

National Natural Science Foundation["61904208","62104091"] ; Guangdong Basic and Applied Basic Research Foundation["2022A1515011272","2022A1515011064"] ; Shenzhen Science and Technology Program[JCYJ20190807155411277] ; Shenzhen Fundamental Research Program NSQKJJ["K21799128","K21799131"]

Automation & Control Systems ; Computer Science ; Robotics

Automation & Control Systems ; Computer Science, Artificial Intelligence ; Robotics

WOS:000871946100001

WILEY

Web of Science

1.Sun Yat Sen Univ, Sch Mat, State Key Lab Optoelect Mat & Technol, Guangzhou 510275, Peoples R China
2.Southern Univ Sci & Technol, Sch Microelect, Shenzhen 518055, Peoples R China

Li, Fang Zhou,Liu, Hong Rui,Guo, Jian Miao,et al. An Artificial Thermal Nociceptor Based on Xanthan Gum-Gated Synaptic Transistors to Emulate Human Thermal Nociception[J]. ADVANCED INTELLIGENT SYSTEMS,2022.

Li, Fang Zhou.,Liu, Hong Rui.,Guo, Jian Miao.,Zhou, Xin Yi.,Liu, Ke Kang.,...&Liu, Yang Hui.(2022).An Artificial Thermal Nociceptor Based on Xanthan Gum-Gated Synaptic Transistors to Emulate Human Thermal Nociception.ADVANCED INTELLIGENT SYSTEMS.

Li, Fang Zhou,et al."An Artificial Thermal Nociceptor Based on Xanthan Gum-Gated Synaptic Transistors to Emulate Human Thermal Nociception".ADVANCED INTELLIGENT SYSTEMS (2022).