Reconstructing the portal vein through a posterior pancreatic tunnel: New choice for portal vein thrombosis during liver transplantation

Zhao, Dong1,2,3,4; Huang, Yi-Ming1,2; Liang, Zi-Ming1,2; Zhang, Kang-Jun1,2; Fang, Tai-Shi1,2; Yan, Xu1,2; Jin, Xin1,2; Zhang, Yi1,2; Tang, Jian-Xin1,2; Xie, Lin-Jie1,2; Zeng, Xin-Chen1,2

2022-10-27

10.4240/wjgs.v14.i10.1131

World Journal of Gastrointestinal Surgery   Impact Factor & Quartile

1948-9366

BACKGROUNDThrombectomy and anatomical anastomosis (TAA) has long been considered the optimal approach to portal vein thrombosis (PVT) in liver transplantation (LT). However, TAA and the current approach for non-physiological portal reconstructions are associated with a higher rate of complications and mortality in some cases.AIMTo describe a new choice for reconstructing the portal vein through a posterior pancreatic tunnel (RPVPPT) to address cases of unresectable PVT.METHODSBetween August 2019 and August 2021, 245 adult LTs were performed. Forty-five (18.4%) patients were confirmed to have PVT before surgery, among which seven underwent PV reconstruction via the RPVPPT approach. We retrospectively analyzed the surgical procedure and postoperative complications of these seven recipients that underwent PV reconstruction due to PVT.RESULTSDuring the procedure, PVT was found in all the seven cases with significant adhesion to the vascular wall and could not be dissected. The portal vein proximal to the superior mesenteric vein was damaged in one case when attempting thrombolectomy, resulting in massive bleeding. LT was successfully performed in all patients with a mean duration of 585 min (range 491-756 min) and mean intraoperative blood loss of 800 mL (range 500-3000 mL). Postoperative complications consisted of chylous leakage (n = 3), insufficient portal venous flow to the graft (n = 1), intra-abdominal hemorrhage (n = 1), pulmonary infection (n = 1), and perioperative death (n = 1). The remaining six patients survived at 12-17 mo follow-up.CONCLUSIONThe RPVPPT technique might be a safe and effective surgical procedure during LT for complex PVT. However, follow-up studies with large samples are still warranted due to the relatively small number of cases.

Liver transplantation Portal vein thrombosis Portal vein reconstruction Retropancreatic tunnel Computer tomography angiography Three-dimensional visualization

SCI

English

First ; Corresponding

Shenzhen Scientific Research Project["G2021008","G2022008"] ; Shenzhen Key Medical Discipline Construction Fund[SZXK079] ; Shenzhen Science and Technology Research and Development Fund["JCYJ20190809165813331","JCYJ20210324131809027"]

Gastroenterology & Hepatology ; Surgery

Gastroenterology & Hepatology ; Surgery

WOS:000884427700004

BAISHIDENG PUBLISHING GROUP INC

Web of Science

1.Southern Univ Sci & Technol, Peoples Hosp Shenzhen 3, Natl Clin Res Ctr Infect Dis, Affiliated Hosp 2,Dept Liver Surg, Shenzhen 518000, Guangdong, Peoples R China
2.Southern Univ Sci & Technol, Peoples Hosp Shenzhen 3, Natl Clin Res Ctr Infect Dis, Affiliated Hosp 2,Organ Transplantat Ctr, Shenzhen 518000, Guangdong, Peoples R China
3.Southern Univ Sci & Technol, Peoples Hosp Shenzhen 3, Natl Clin Res Ctr Infect Dis, Affiliated Hosp 2,Dept Liver Surg, 29 Bulan Rd, Shenzhen 518000, Guangdong, Peoples R China
4.Southern Univ Sci & Technol, Peoples Hosp Shenzhen 3, Natl Clin Res Ctr Infect Dis, Affiliated Hosp 2,Organ Transplantat Ctr, 29 Bulan Rd, Shenzhen 518000, Guangdong, Peoples R China

Zhao, Dong,Huang, Yi-Ming,Liang, Zi-Ming,et al. Reconstructing the portal vein through a posterior pancreatic tunnel: New choice for portal vein thrombosis during liver transplantation[J]. World Journal of Gastrointestinal Surgery,2022,14(10).

Zhao, Dong.,Huang, Yi-Ming.,Liang, Zi-Ming.,Zhang, Kang-Jun.,Fang, Tai-Shi.,...&Zeng, Xin-Chen.(2022).Reconstructing the portal vein through a posterior pancreatic tunnel: New choice for portal vein thrombosis during liver transplantation.World Journal of Gastrointestinal Surgery,14(10).

Zhao, Dong,et al."Reconstructing the portal vein through a posterior pancreatic tunnel: New choice for portal vein thrombosis during liver transplantation".World Journal of Gastrointestinal Surgery 14.10(2022).