Topological approach of liver segmentation based on 3D visualization technology in surgical planning for split liver transplantation

Zhao, Dong1,2,3; Zhang, Kang-Jun1; Fang, Tai-Shi1; Yan, Xu1; Jin, Xin1; Liang, Zi-Ming1; Tang, Jian-Xin1; Xie, Lin-Jie1

2022-10-27

10.4240/wjgs.v14.i10.1141

World Journal of Gastrointestinal Surgery   Impact Factor & Quartile

1948-9366

BACKGROUNDSplit liver transplantation (SLT) is a complex procedure. The left-lateral and right tri-segment splits are the most common surgical approaches and are based on the Couinaud liver segmentation theory. Notably, the liver surface following right tri-segment splits may exhibit different degrees of ischemic changes related to the destruction of the local portal vein blood flow topology. There is currently no consensus on preoperative evaluation and predictive strategy for hepatic segmental necrosis after SLT.AIMTo investigate the application of the topological approach in liver segmentation based on 3D visualization technology in the surgical planning of SLT.METHODSClinical data of 10 recipients and 5 donors who underwent SLT at Shenzhen Third People's Hospital from January 2020 to January 2021 were retrospectively analyzed. Before surgery, all the donors were subjected to 3D modeling and evaluation. Based on the 3D-reconstructed models, the liver splitting procedure was simulated using the liver segmentation system described by Couinaud and a blood flow topology liver segmentation (BFTLS) method. In addition, the volume of the liver was also quantified. Statistical indexes mainly included the hepatic vasculature and expected volume of split grafts evaluated by 3D models, the actual liver volume, and the ischemia state of the hepatic segments during the actual surgery.RESULTSAmong the 5 cases of split liver surgery, the liver was split into a left-lateral segment and right tri-segment in 4 cases, while 1 case was split using the left and right half liver splitting. All operations were successfully implemented according to the preoperative plan. According to Couinaud liver segmentation system and BFTLS methods, the volume of the left lateral segment was 359.00 & PLUSMN; 101.57 mL and 367.75 & PLUSMN; 99.73 mL, respectively, while that measured during the actual surgery was 397.50 & PLUSMN; 37.97 mL. The volume of segment IV (the portion of ischemic liver lobes) allocated to the right tri-segment was 136.31 & PLUSMN; 86.10 mL, as determined using the topological approach to liver segmentation. However, during the actual surgical intervention, ischemia of the right tri-segment section was observed in 4 cases, including 1 case of necrosis and bile leakage, with an ischemic liver volume of 238.7 mL.CONCLUSION3D visualization technology can guide the preoperative planning of SLT and improve accuracy during the intervention. The simulated operation based on 3D visualization of blood flow topology may be useful to predict the degree of ischemia in the liver segment and provide a reference for determining whether the ischemic liver tissue should be removed during the surgery.

Three-dimensional visualization Couinaud liver segmentation Blood flow topology liver segmentation Split liver transplantation Surgical planning

SCI

English

First ; Corresponding

Gastroenterology & Hepatology ; Surgery

Gastroenterology & Hepatology ; Surgery

WOS:000884427700005

BAISHIDENG PUBLISHING GROUP INC

Web of Science

1.Second Affiliated Hosp Southern Univ Sci & Technol, Peoples Hosp Shenzhen 3, Organ Transplantat Ctr, Natl Clin Res Ctr Infect Dis, Shenzhen 518000, Guangdong, Peoples R China
2.Southern Univ Sci & Technol, Affiliated Hosp 2, Peoples Hosp Shenzhen 3, Natl Clin Res Ctr Infect Dis,Dept Liver Surg, 29 Bulan Rd, Shenzhen 518000, Guangdong, Peoples R China
3.Southern Univ Sci & Technol, Affiliated Hosp 2, Peoples Hosp Shenzhen 3, Natl Clin Res Ctr Infect Dis,Organ Transplantat Ct, 29 Bulan Rd, Shenzhen 518000, Guangdong, Peoples R China

Zhao, Dong,Zhang, Kang-Jun,Fang, Tai-Shi,et al. Topological approach of liver segmentation based on 3D visualization technology in surgical planning for split liver transplantation[J]. World Journal of Gastrointestinal Surgery,2022,14(10).

Zhao, Dong.,Zhang, Kang-Jun.,Fang, Tai-Shi.,Yan, Xu.,Jin, Xin.,...&Xie, Lin-Jie.(2022).Topological approach of liver segmentation based on 3D visualization technology in surgical planning for split liver transplantation.World Journal of Gastrointestinal Surgery,14(10).

Zhao, Dong,et al."Topological approach of liver segmentation based on 3D visualization technology in surgical planning for split liver transplantation".World Journal of Gastrointestinal Surgery 14.10(2022).