Low-Photon Counts Coherent Modulation Imaging via Generalized Alternating Projection Algorithm

Meng,Sun1; Tao,Liu2; George,Barbastathis3; Yincheng,Qi1; Fucai,Zhang2

2022-11-11

10.3390/app122211436

Applied Sciences-Basel   Impact Factor & Quartile

2076-3417

2076-3417

Phase contrast imaging is advantageous for mitigating radiation damage to samples, such as biological specimens. For imaging at nanometer or atomic resolution, the required flux on samples increases dramatically and can easily exceed the sample damage threshold. Coherent modulation imaging (CMI) can provide quantitative absorption and phase images of samples at diffraction-limited resolution with fast convergence. When used for radiation-sensitive samples, CMI experiments need to be conducted under low illumination flux for high resolution. Here, an algorithmic framework is proposed for CMI involving generalized alternating projection and total variation constraint. A five-to-ten-fold lower photon requirement can be achieved for near-field or far-field experiment dataset. The work would make CMI more applicable to the dynamics study of radiation-sensitive samples.

sample damage phase imaging optimization algorithm

SCI

English

Others

Natural National Science Foundation of China (NSFC)["12074167","11775105"] ; Shenzhen Key Laboratory of Robotics Perception and Intelligence[ZDSYS20200810171800001] ; Shenzhen Science and Technology Program[KQTD20170810110313773] ; Centers forMechanical Engineering Research and Education at MIT and SUSTech (MechERE Centers at MIT and SUSTech)[6941806] ; S&T Program of Hebei[SZX2020034]

Chemistry ; Engineering ; Materials Science ; Physics

Chemistry, Multidisciplinary ; Engineering, Multidisciplinary ; Materials Science, Multidisciplinary ; Physics, Applied

WOS:000887115300001

MDPI AG

人工提交

1.Hebei Key Laboratory of Power Internet of Things Technology and the Department of Electronics and Communication Engineering
2.Shenzhen Key Laboratory of Robotics Perception and Intelligence and the Department of Electrical and Electronic Engineering
3.Department of Mechanical Engineering, Massachusetts Institute of Technology

Meng,Sun,Tao,Liu,George,Barbastathis,et al. Low-Photon Counts Coherent Modulation Imaging via Generalized Alternating Projection Algorithm[J]. Applied Sciences-Basel,2022,12(22):11436.

Meng,Sun,Tao,Liu,George,Barbastathis,Yincheng,Qi,&Fucai,Zhang.(2022).Low-Photon Counts Coherent Modulation Imaging via Generalized Alternating Projection Algorithm.Applied Sciences-Basel,12(22),11436.

Meng,Sun,et al."Low-Photon Counts Coherent Modulation Imaging via Generalized Alternating Projection Algorithm".Applied Sciences-Basel 12.22(2022):11436.