Transition metal-catalyzed enantioselective C–P coupling reactions for the construction of P-stereogenic centers

Luan，Cheng1,2,3; Yang，Chang Jiang1; Liu，Lin1; Gu，Qiang Shuai3; Liu，Xin Yuan2

2022-11-17

10.1016/j.checat.2022.09.048

Chem Catalysis   Impact Factor & Quartile

2667-1107

2667-1093

The transition metal-catalyzed C–P coupling reaction represents an effective strategy for the construction of P-stereogenic centers. These reactions involve different stereochemical mechanistic details depending on the phosphorus starting materials employed. The stereospecific transition metal-catalyzed C–P coupling of enantioenriched P-stereogenic compounds was mainly investigated in the early days. With the development of asymmetric catalysis, corresponding efficient kinetic resolution and dynamic kinetic asymmetric C–P coupling of racemic P-stereogenic starting compounds have recently been disclosed. This perspective discusses the impressive advances and provides an outlook on the directions of further developments.

C–P coupling P-stereogenic centers SDG3: Good health and well-being secondary phosphine secondary phosphine oxide transition metal catalysis

English

Others

Guangdong Provincial Key Laboratory Of Catalysis[2020B121201002];National Key Research and Development Program of China[2021YFF0701604];National Key Research and Development Program of China[2021YFF0701704];National Natural Science Foundation of China[21831002];National Natural Science Foundation of China[22001109];National Natural Science Foundation of China[22025103];National Natural Science Foundation of China[22101122];National Natural Science Foundation of China[22271133];

2-s2.0-85141942430

Scopus

1.School of Science and Institute of Scientific Research,Great Bay University,Dongguan,523000,China
2.Shenzhen Grubbs Institute and Department of Chemistry,Guangdong Provincial Key Laboratory of Catalysis,Southern University of Science and Technology,Shenzhen,518055,China
3.Academy for Advanced Interdisciplinary Studies and Department of Chemistry,Southern University of Science and Technology,Shenzhen,518055,China

Luan，Cheng,Yang，Chang Jiang,Liu，Lin,等. Transition metal-catalyzed enantioselective C–P coupling reactions for the construction of P-stereogenic centers[J]. Chem Catalysis,2022,2(11):2876-2888.

Luan，Cheng,Yang，Chang Jiang,Liu，Lin,Gu，Qiang Shuai,&Liu，Xin Yuan.(2022).Transition metal-catalyzed enantioselective C–P coupling reactions for the construction of P-stereogenic centers.Chem Catalysis,2(11),2876-2888.

Luan，Cheng,et al."Transition metal-catalyzed enantioselective C–P coupling reactions for the construction of P-stereogenic centers".Chem Catalysis 2.11(2022):2876-2888.