Deficiency and excess of groundwater iodine and their health associations

Ma，Ruoqi1,2,3; Yan，Mingquan1; Han，Peng1; Wang，Ting1,4; Li，Bin1,4; Zhou，Shungui5; Zheng，Tong1; Hu，Yandi1; Borthwick，Alistair G.L.6,7; Zheng，Chunmiao8; Ni，Jinren1,2

2022-12-01

10.1038/s41467-022-35042-6

Nature Communications   Impact Factor & Quartile

2041-1723

More than two billion people worldwide have suffered thyroid disorders from either iodine deficiency or excess. By creating the national map of groundwater iodine throughout China, we reveal the spatial responses of diverse health risks to iodine in continental groundwater. Greater non-carcinogenic risks relevant to lower iodine more likely occur in the areas of higher altitude, while those associated with high groundwater iodine are concentrated in the areas suffered from transgressions enhanced by land over-use and intensive anthropogenic overexploitation. The potential roles of groundwater iodine species are also explored: iodide might be associated with subclinical hypothyroidism particularly in higher iodine regions, whereas iodate impacts on thyroid risks in presence of universal salt iodization exhibit high uncertainties in lower iodine regions. This implies that accurate iodine supply depending on spatial heterogeneity and dietary iodine structure optimization are highly needed to mitigate thyroid risks in iodine-deficient and -excess areas globally.

SCI

English

NI Journal Papers

Others

National Outstanding Youth Science Fund Project of National Natural Science Foundation of China[51721006];National Outstanding Youth Science Fund Project of National Natural Science Foundation of China[92047303];

Science & Technology - Other Topics

Multidisciplinary Sciences

WOS:000890398000019

NATURE PORTFOLIO

2-s2.0-85142893135

Scopus

1.College of Environmental Sciences and Engineering,Peking University; Key Laboratory of Water and Sediment Sciences,Ministry of Education,Beijing,100871,China
2.Eco-environment and Resource Efficiency Research Laboratory,School of Environment and Energy,Peking University Shenzhen Graduate School,Shenzhen,518055,China
3.General Institute of Water Resources and Hydropower Planning and Design,Ministry of Water Resources,Beijing,100120,China
4.State Environmental Protection Key Laboratory of All Materials Fluxes in River Ecosystems,Peking University,Beijing,100871,China
5.Provincial Key Laboratory of Soil Environment Health and Regulation,Fujian Agriculture and Forestry University,Fuzhou,350002,China
6.Institute of Infrastructure and Environment,School of Engineering,The University of Edinburgh,Edinburgh,EH9 3JL,United Kingdom
7.School of Engineering,Mathematics and Computing,University of Plymouth,Plymouth,PL8 4AA,United Kingdom
8.State Environmental Protection Key Laboratory for Integrated Control of Groundwater and Surface Water Pollution in Watershed,Southern University of Science and Technology,Shenzhen,518055,China

Ma，Ruoqi,Yan，Mingquan,Han，Peng,et al. Deficiency and excess of groundwater iodine and their health associations[J]. Nature Communications,2022,13(1).

Ma，Ruoqi.,Yan，Mingquan.,Han，Peng.,Wang，Ting.,Li，Bin.,...&Ni，Jinren.(2022).Deficiency and excess of groundwater iodine and their health associations.Nature Communications,13(1).

Ma，Ruoqi,et al."Deficiency and excess of groundwater iodine and their health associations".Nature Communications 13.1(2022).