| Title | Homogeneous Dearomative Hydrogenation with a Co/P4N2 Catalyst: A Nucleophilic Approach |
| Author | |
| Corresponding Author | Zhang, Xumu; Wen, Jialin |
| Publication Years | 2022-12-01
|
| DOI | |
| Source Title | |
| ISSN | 0947-6539
|
| EISSN | 1521-3765
|
| Abstract | Arene hydrogenation is the most straightforward method to prepare carbo- and heterocycles. However, the high resonance energy prevents aromatic substrates from hydrogenation. Herein the homogeneous, nucleophilic hydrogenation of less electron-rich arenes and heteroarenes is reported. The Co(P4N2)H species that has been demonstrated to be a strong hydride donor could deliver a hydride ion to the cyano (hetero)arene substrates. Deuterium labeling experiments supported a Michael-type reaction pathway. Theoretical analyses have been conducted to investigate the hydricity of the catalytically active CoH species and the electrophilicity of the arene substrates. An outlook for the synthesis of more challenging substituted benzenes was proposed based on the in silico modification of the CoH species. |
| Keywords | |
| URL | [Source Record] |
| Indexed By | |
| Language | English
|
| SUSTech Authorship | First
; Corresponding
|
| Funding Project | Chemistry and Chemical Engineering Guangdong Laboratory["2132013","2011006"]
; Guangdong Provincial Key Laboratory of Catalysis[2020B121201002]
; China Postdoctoral Science Foundation[2020M672690]
|
| WOS Research Area | Chemistry
|
| WOS Subject | Chemistry, Multidisciplinary
|
| WOS Accession No | WOS:000902954400001
|
| Publisher | |
| ESI Research Field | CHEMISTRY
|
| Data Source | Web of Science
|
| Citation statistics |
Cited Times [WOS]:0
|
| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/424877 |
| Department | Department of Chemistry |
| Affiliation | 1.Southern Univ Sci & Technol, Dept Chem, Guangdong Prov Key Lab Catalysis, 1088 Xueyuan Rd, Shenzhen 518055, Peoples R China 2.Chem & Chem Engn Guangdong Lab, Shantou 515031, Peoples R China |
| First Author Affilication | Department of Chemistry |
| Corresponding Author Affilication | Department of Chemistry |
| First Author's First Affilication | Department of Chemistry |
| Recommended Citation GB/T 7714 |
Zhang, Shaoke,Zhou, Rong,Duan, Ya-Nan,et al. Homogeneous Dearomative Hydrogenation with a Co/P4N2 Catalyst: A Nucleophilic Approach[J]. CHEMISTRY-A EUROPEAN JOURNAL,2022.
|
| APA |
Zhang, Shaoke,Zhou, Rong,Duan, Ya-Nan,Zhou, Yang,Zhang, Xumu,&Wen, Jialin.(2022).Homogeneous Dearomative Hydrogenation with a Co/P4N2 Catalyst: A Nucleophilic Approach.CHEMISTRY-A EUROPEAN JOURNAL.
|
| MLA |
Zhang, Shaoke,et al."Homogeneous Dearomative Hydrogenation with a Co/P4N2 Catalyst: A Nucleophilic Approach".CHEMISTRY-A EUROPEAN JOURNAL (2022).
|
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