Title | Transcranial random noise stimulation over the left dorsolateral prefrontal cortex attenuates pain expectation and perception |
Author | |
Corresponding Author | Jin, Richu |
Publication Years | 2023-03-01
|
DOI | |
Source Title | |
ISSN | 1388-2457
|
EISSN | 1872-8952
|
Volume | 147Pages:1-10 |
Abstract | Objective: The dorsolateral prefrontal cortex (DLPFC) has been increasingly used as a neuromodulatory target in pain management. Transcranial random noise stimulation (tRNS) was shown to effectively ele-vate cortical excitability. Hence, this study aimed to characterize how tRNS over the left DLPFC affects pain expectation and perception, as well as the efficacy of conditioned-pain modulation (CPM) that reflects the function of the endogenous pain-inhibitory pathway. Methods: Using a randomized, double-blinded, and sham-controlled design, healthy participants were randomly recruited to receive tRNS with a direct current offset or sham stimulation. Their expectations and perceptions of painful electrocutaneous stimuli, as well as CPM efficacy were assessed before, imme-diately after, and 30 min after tRNS. Results: Compared with sham stimulation, perceived-pain ratings to the painful stimuli, and expected -pain ratings before painful stimuli, attenuated immediately after tRNS, whereas this analgesic effect was ineffective 30 min after tRNS. Importantly, the immediate analgesia induced by tRNS could be accounted for by tRNS effect on attenuating expected-pain ratings before certain painful stimuli. However, CPM efficacy was not significantly affected by tRNS. Conclusions: These results demonstrate analgesia immediately after applying tRNS over the left DLPFC. Significance: This study provides evidence for analgesia of DLPFC-tRNS on an experimental pain model.(c) 2022 International Federation of Clinical Neurophysiology. Published by Elsevier B.V. All rights reserved. |
Keywords | |
URL | [Source Record] |
Indexed By | |
Language | English
|
SUSTech Authorship | Corresponding
|
Funding Project | Ministry of Science and Technology of China[2022ZD0206400]
; National Natural Science Foundation of China["32271105","32200900","62101236"]
; Shenzhen Natural Science Fund[20200812113251002]
|
WOS Research Area | Neurosciences & Neurology
|
WOS Subject | Clinical Neurology
; Neurosciences
|
WOS Accession No | WOS:000919660700001
|
Publisher | |
ESI Research Field | NEUROSCIENCE & BEHAVIOR
|
Scopus EID | 2-s2.0-85146002951
|
Data Source | Web of Science
|
Citation statistics |
Cited Times [WOS]:0
|
Document Type | Journal Article |
Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/431008 |
Department | Department of Computer Science and Engineering |
Affiliation | 1.Shenzhen Univ, Sch Psychol, Shenzhen, Guangdong, Peoples R China 2.Shenzhen Prevent & Treatment Ctr Occupat Dis, Med Rehabil Ctr, Shenzhen, Guangdong, Peoples R China 3.Southern Univ Sci & Technol, Dept Comp Sci & Engn, Shenzhen, Guangdong, Peoples R China 4.Southern Univ Sci & Technol, Dept Comp Sci & Engn, Xueyuan Ave 1088, Shenzhen 518055, Peoples R China |
Corresponding Author Affilication | Department of Computer Science and Engineering |
Recommended Citation GB/T 7714 |
Li, Xiaoyun,Yao, Junjie,Lin, Xinxin,et al. Transcranial random noise stimulation over the left dorsolateral prefrontal cortex attenuates pain expectation and perception[J]. CLINICAL NEUROPHYSIOLOGY,2023,147:1-10.
|
APA |
Li, Xiaoyun,Yao, Junjie,Lin, Xinxin,Chen, Shengxiong,Jin, Richu,&Peng, Weiwei.(2023).Transcranial random noise stimulation over the left dorsolateral prefrontal cortex attenuates pain expectation and perception.CLINICAL NEUROPHYSIOLOGY,147,1-10.
|
MLA |
Li, Xiaoyun,et al."Transcranial random noise stimulation over the left dorsolateral prefrontal cortex attenuates pain expectation and perception".CLINICAL NEUROPHYSIOLOGY 147(2023):1-10.
|
Files in This Item: | There are no files associated with this item. |
|
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
Edit Comment