Protocol to analyze population structure and migration history based on human genome variation data
|Corresponding Author||Li，Shuai Cheng|
We describe a protocol to integrate genome variation data from different datasets and explore the population structure and migration history of human populations. This protocol provides semi-automated scripts to perform and visualize the effect of variant filtering strategy on eliminating batch effects, principal component analysis, ancestry component analysis, historical population effective size inference, and migration and isolation analysis based on independent biallelic SNPs, genotype likelihoods, and haplotypes. The protocol can be adapted to variation data from other sources. For complete details on the use and execution of this protocol, please refer to Zhang et al. (2022).
|WOS Accession No|
Cited Times [WOS]:1
|Document Type||Journal Article|
|Department||School of Medicine|
1.Department of Computer Science,City University of Hong Kong,Kowloon,999077,Hong Kong
2.Shenzhen Byoryn Technology Co.,Ltd.,Shenzhen,518000,China
3.Peking University Shenzhen Hospital,Shenzhen,1120 Lianhua Road,518036,China
4.School of Medicine,Southern University of Science and Technology,Shenzhen,1088 Xueyuan Avenue,518055,China
5.Department of Cardiology,Zhuhai People's Hospital (Zhuhai Hospital Affiliated with Jinan University),Zhuhai,No. 79 Kanning Road,519000,China
Zhao，Zicheng,Wang，Yinan,Zhang，Zhe,et al. Protocol to analyze population structure and migration history based on human genome variation data[J]. STAR Protocols,2023,4(1).
Zhao，Zicheng,Wang，Yinan,Zhang，Zhe,&Li，Shuai Cheng.(2023).Protocol to analyze population structure and migration history based on human genome variation data.STAR Protocols,4(1).
Zhao，Zicheng,et al."Protocol to analyze population structure and migration history based on human genome variation data".STAR Protocols 4.1(2023).
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