| Title | Differential antigen expression between human apocrine sweat glands and eccrine sweat glands |
| Author | |
| Corresponding Author | Li, Haihong |
| Publication Years | 2023
|
| DOI | |
| Source Title | |
| ISSN | 1121-760X
|
| EISSN | 2038-8306
|
| Volume | 67Issue:1 |
| Abstract | Bromhidrosis has a great negative impact on personal occupation and social psychology. It is not yet clear whether bromhidrosis is caused by apocrine sweat glands or the co-action of apocrine sweat glands and eccrine sweat glands. To distinguish between apocrine sweat glands and eccrine sweat glands, specific antigen markers for apocrine sweat glands and eccrine sweat glands must be found first. In the study, we detected the expression of keratin (K) 7, K18, K19, Na+-K+-2Cl- cotransporter 1 (NKCC1), carbonic anhydrase II (CAII), Forkhead transcription factor a1 (Foxa1), homeobox transcription factor engrailed homeobox1 (En1), gross cystic disease fluid protein-15 (GCDFP-15), mucin-1 (MUC-1), cluster of differentiation 15 (CD15) and apolipoprotein (APOD) in eccrine sweat glands and apocrine sweat glands by immunofluorescence staining. The results showed that K7, K18, K19, Foxa1, GCDFP-15 and MUC-1 were expressed in both apocrine and eccrine sweat glands, CD15 and APOD were only expressed in apocrine sweat glands, and CAII, NKCC1 and En1 were only expressed in eccrine sweat glands. We conclude that CD15 and APOD can serve as specific markers for apoc-rine sweat glands, while CAII, NKCC1 and En1 can serve as specific markers for eccrine sweat glands to dif-ferentiate the two sweat glands. |
| Keywords | |
| URL | [Source Record] |
| Indexed By | |
| Language | English
|
| SUSTech Authorship | Corresponding
|
| Funding Project | null[82172231]
; null[82172211]
; null[81830064]
|
| WOS Research Area | Cell Biology
|
| WOS Subject | Cell Biology
|
| WOS Accession No | WOS:000921292300003
|
| Publisher | |
| ESI Research Field | BIOLOGY & BIOCHEMISTRY
|
| Data Source | Web of Science
|
| Citation statistics |
Cited Times [WOS]:0
|
| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/475011 |
| Department | School of Medicine 南方科技大学医院 |
| Affiliation | 1.Hubei Univ Med, Taihe Hosp, Dept Wound Repair & Dermatol Surg, Shiyan, Hubei, Peoples R China 2.Southern Univ Sci & Technol, Dept Mental Hlth, Southern Univ Sci & Technol Hosp, Sch Med, Shenzhen, Guangdong, Peoples R China 3.Southern Univ Sci & Technol, Sch Med, Dept Wound Repair, Inst Wound Repair & Regenerat Med,Southern Univ Sc, Shenzhen, Guangdong, Peoples R China 4.Hubei Univ Med, Taihe Hosp, Dept Wound Repair & Dermatol Surg, 32 South Renmin Rd, Shiyan 442000, Hubei, Peoples R China |
| Corresponding Author Affilication | School of Medicine |
| Recommended Citation GB/T 7714 |
Cao, Manxiu,Zhang, Lei,Cheng, Jiaqi,et al. Differential antigen expression between human apocrine sweat glands and eccrine sweat glands[J]. EUROPEAN JOURNAL OF HISTOCHEMISTRY,2023,67(1).
|
| APA |
Cao, Manxiu.,Zhang, Lei.,Cheng, Jiaqi.,Wang, Cangyu.,Zhao, Junhong.,...&Li, Haihong.(2023).Differential antigen expression between human apocrine sweat glands and eccrine sweat glands.EUROPEAN JOURNAL OF HISTOCHEMISTRY,67(1).
|
| MLA |
Cao, Manxiu,et al."Differential antigen expression between human apocrine sweat glands and eccrine sweat glands".EUROPEAN JOURNAL OF HISTOCHEMISTRY 67.1(2023).
|
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