The Impact of Contrast-Associated Acute Kidney Injury on All-Cause Mortality in Older Patients After Coronary Angiography:A 7.5-year Follow-Up

Guo, Wei1,2,3; Liu, Jin2,3; He, Yibo2,3; Lei, Li4; Guo, Zhaodong5; Song, Feier6; Zhou, Ziyou3,7; Liu, Wenhai8; Zhong, Xian8; Chen, Shiqun9; Rao, Lifen1,10; Liu, Yong2,3,11

2023-02-01

10.1177/00033197231155610

ANGIOLOGY   Impact Factor & Quartile

0003-3197

1940-1574

Older patients (>= 75 years) after coronary angiography constitute an increasing proportion, but only limited data are available regarding the prognosis of geriatric contrast-associated acute kidney injury (CA-AKI). Patients (>= 75 years) undergoing coronary angiography between December 2010 and September 2013 were consecutively enrolled. CA-AKI was defined as an increase in serum creatinine of 25% or .5 mg/dL from the baseline within 48-72 h of contrast exposure. All-cause mortality was assessed during median 7.5 years (interquartile range [IQR] 6.7-8.7 years) follow-up period. In total, 571 patients aged >75 years undergoing coronary angiography were enrolled in a single center study; 82 (14.4%) patients had CA-AKI. The all-cause mortality during the median 7.5 years follow-up period was 22.0% in patients with CA-AKI and 13.1% in patients without CA-AKI (P = .015). After adjusting for potential confounding factors, the multivariable analysis indicated that CA-AKI was related to an increased risk of all-cause mortality during the median 7.5-year follow-up (hazard ratio [HR]: 2.46; 95% CI: 1.29-4.7; P = .006). CA-AKI is a significant and independent predictor of long-term mortality for patients aged over 75 years who underwent coronary angiography.

contrast-associated acute kidney injury older people long-term mortality coronary angiography

SCI

English

Others

Cardiovascular System & Cardiology

Peripheral Vascular Disease

WOS:000928231700001

SAGE PUBLICATIONS INC

CLINICAL MEDICINE

Web of Science

1.Southern Med Univ, Guangdong Prov Peoples Hosp, Guangdong Acad Med Sci, Guangdong Prov Geriatr Inst, Guangzhou, Peoples R China
2.Guangdong Prov Peoples Hosp, Guangdong Cardiovasc Inst, Guangdong Acad Med Sci, Dept Cardiol, Guangzhou, Peoples R China
3.Southern Med Univ, Guangdong Prov Peoples Hosp, Guangdong Cardiovasc Inst, Guangdong Acad Med Sci,Dept Guangdong Prov Key Lab, Guangzhou, Peoples R China
4.Southern Med Univ, Dept Cardiol, Nanfang Hosp, Guangzhou, Peoples R China
5.Southern Univ Sci & Technol, Jinan Univ, Shenzhen Peoples Hosp, Affiliated Hosp 1,Dept Cardiol,Clin Med Coll 2, Shenzhen, Peoples R China
6.Southern Med Univ, Guangdong Prov Peoples Hosp, Guangdong Acad Med Sci, Dept Emergency & Crit Care Med, Guangzhou, Peoples R China
7.South China Univ Technol, Sch Med, Guangzhou, Peoples R China
8.Guangdong Med Univ, Coll Pharm, Zhanjiang, Peoples R China
9.Southern Med Univ, Guangdong Prov Peoples Hosp, Guangdong Acad Med Sci, Global Hlth Res Ctr, Guangzhou, Peoples R China
10.Southern Med Univ, Guangdong Prov Peoples Hosp, Guangdong Prov Geriatr Inst, Guangdong Acad Med Sci, 106 Zhongshan Second Rd, Guangzhou 510100, Peoples R China
11.Southern Med Univ, Guangdong Prov Peoples Hosp, Guangdong Cardiovasc Inst, Guangdong Acad Med Sci,Dept Cardiol, 106 Zhongshan Second Rd, Guangzhou 510100, Peoples R China

Guo, Wei,Liu, Jin,He, Yibo,et al. The Impact of Contrast-Associated Acute Kidney Injury on All-Cause Mortality in Older Patients After Coronary Angiography:A 7.5-year Follow-Up[J]. ANGIOLOGY,2023.

Guo, Wei.,Liu, Jin.,He, Yibo.,Lei, Li.,Guo, Zhaodong.,...&Liu, Yong.(2023).The Impact of Contrast-Associated Acute Kidney Injury on All-Cause Mortality in Older Patients After Coronary Angiography:A 7.5-year Follow-Up.ANGIOLOGY.

Guo, Wei,et al."The Impact of Contrast-Associated Acute Kidney Injury on All-Cause Mortality in Older Patients After Coronary Angiography:A 7.5-year Follow-Up".ANGIOLOGY (2023).