中文版 | English
Title

Novel roles of RNA-binding proteins in drug resistance of breast cancer: from molecular biology to targeting therapeutics

Author
Corresponding AuthorYao, Herui; Gong, Chang
Publication Years
2023-02-09
DOI
Source Title
EISSN
2058-7716
Volume9Issue:1
Abstract
Therapy resistance remains a huge challenge for current breast cancer treatments. Exploring molecular mechanisms of therapy resistance might provide therapeutic targets for patients with advanced breast cancer and improve their prognosis. RNA-binding proteins (RBPs) play an important role in regulating therapy resistance. Here we summarize the functions of RBPs, highlight their tremendously important roles in regulating therapy sensitivity and resistance and we also reveal current therapeutic approaches reversing abnormal functions of RBPs in breast cancer.
URL[Source Record]
Indexed By
Language
English
SUSTech Authorship
Others
Funding Project
Natural Science Foundation of China["81872139","82072907"] ; Project of The Beijing Xisike Clinical Oncology Research Foundation[Y-Roche2019/2-0078\Y-pierrefabre202102-0107] ; Technology Development Program of Guangdong province[2021A0505030082] ; Project of The Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation[2020B1212060018] ; null[2022005]
WOS Research Area
Cell Biology
WOS Subject
Cell Biology
WOS Accession No
WOS:000931464000001
Publisher
Data Source
Web of Science
Citation statistics
Cited Times [WOS]:2
Document TypeJournal Article
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/489978
DepartmentShenzhen People's Hospital
Affiliation
1.Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Guangdong Prov Key Lab Malignant Tumor Epigenet &, Guangzhou 510120, Peoples R China
2.Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Breast Tumor Ctr, Guangzhou 510120, Peoples R China
3.Jinan Univ, Southern Univ Sci & Technol, Shenzhen Peoples Hosp, Affiliated Hosp 1,Dept Breast & Thyroid Surg,Clin, Shenzhen 518020, Peoples R China
Recommended Citation
GB/T 7714
Cen, Yinghuan,Chen, Letian,Liu, Zihao,et al. Novel roles of RNA-binding proteins in drug resistance of breast cancer: from molecular biology to targeting therapeutics[J]. CELL DEATH DISCOVERY,2023,9(1).
APA
Cen, Yinghuan.,Chen, Letian.,Liu, Zihao.,Lin, Qun.,Fang, Xiaolin.,...&Gong, Chang.(2023).Novel roles of RNA-binding proteins in drug resistance of breast cancer: from molecular biology to targeting therapeutics.CELL DEATH DISCOVERY,9(1).
MLA
Cen, Yinghuan,et al."Novel roles of RNA-binding proteins in drug resistance of breast cancer: from molecular biology to targeting therapeutics".CELL DEATH DISCOVERY 9.1(2023).
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