中文版 | English
Title

Dihydroartemisinin engages liver fatty acid binding protein and suppresses metastatic hepatocellular carcinoma growth

Author
Corresponding AuthorLok, Chun-Nam; Che, Chi-Ming
Publication Years
2023-02-01
DOI
Source Title
ISSN
1359-7345
EISSN
1364-548X
Abstract
Dihydroartemisinin non-covalently binds liver fatty acid binding protein (FABP1) with micromolar affinity, acts as a FABP1-dependent peroxisome proliferator-activated receptor alpha agonist and inhibits metastatic hepatocellular carcinoma growth.
URL[Source Record]
Indexed By
Language
English
Important Publications
NI Journal Papers
SUSTech Authorship
Corresponding
WOS Research Area
Chemistry
WOS Subject
Chemistry, Multidisciplinary
WOS Accession No
WOS:000931302700001
Publisher
ESI Research Field
CHEMISTRY
Data Source
Web of Science
Citation statistics
Cited Times [WOS]:0
Document TypeJournal Article
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/489983
DepartmentDepartment of Chemistry
Affiliation
1.Cent China Normal Univ, Coll Chem, Natl Key Lab Green Pesticide, Wuhan 430079, Peoples R China
2.Univ Hong Kong, State Key Lab Synthet Chem, Pokfulam Rd, Hong Kong, Peoples R China
3.Univ Hong Kong, Dept Chem, P, R China, Pokfulam Rd, Hong Kong, Peoples R China
4.Lab Synthet Chem, Hong Kong Sci Pk, Hong Kong, Peoples R China
5.Chem Biol Ltd, Hong Kong Sci Pk, Hong Kong, Peoples R China
6.Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Guangdong, Peoples R China
7.Univ Hong Kong, Dept Pathol, Pokfulam Rd, Hong Kong, Peoples R China
Corresponding Author AffilicationDepartment of Chemistry
Recommended Citation
GB/T 7714
Ruan, Mei-Ling,Liu, Yungen,Zhang, Chunlei,et al. Dihydroartemisinin engages liver fatty acid binding protein and suppresses metastatic hepatocellular carcinoma growth[J]. CHEMICAL COMMUNICATIONS,2023.
APA
Ruan, Mei-Ling.,Liu, Yungen.,Zhang, Chunlei.,Mao, Xiaowen.,Hu, Di.,...&Che, Chi-Ming.(2023).Dihydroartemisinin engages liver fatty acid binding protein and suppresses metastatic hepatocellular carcinoma growth.CHEMICAL COMMUNICATIONS.
MLA
Ruan, Mei-Ling,et al."Dihydroartemisinin engages liver fatty acid binding protein and suppresses metastatic hepatocellular carcinoma growth".CHEMICAL COMMUNICATIONS (2023).
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