| Title | Advances in Spheroids and Organoids on a Chip |
| Author | |
| Corresponding Author | Lu, Hongxu; Jin, Dayong |
| Publication Years | 2023-02-01
|
| DOI | |
| Source Title | |
| ISSN | 1616-301X
|
| EISSN | 1616-3028
|
| Abstract | Multicellular spheroids and organoids are promising in vitro 3D models in personalized medicine and drug screening. They replicate the structural and functional characteristics of human organs in vivo. Microfluidic technology and micro-nano fabrication can fulfill the high requirement of the engineering approach in the growing research interest in spheroids and organoids. In this review, spheroids and organoids are comparatively introduced. Then it is illustrated how spheroids- and organoids-on-a-chip technology facilitates their establishment, expansion, and application through spatial-temporal control, mechanical cues modeling, high-throughput analysis, co-culture, multi-tissue interactions, biosensing, and bioimaging integration. The potential opportunities and challenges in developing spheroids- and organoids-on-a-chip technology are finally outlooked. |
| Keywords | |
| URL | [Source Record] |
| Indexed By | |
| Language | English
|
| Important Publications | NI Journal Papers
|
| SUSTech Authorship | Corresponding
|
| Funding Project | Major International (Regional) Joint Research Project of NSFC[51720105015]
; Science and Technology Innovation Commission of Shenzhen[KQTD20170810110913065]
; Australian Research Council Laureate Fellowship Program[FL210100180]
; Nanyang Presidential Fellowship Program[03INS001307C140]
|
| WOS Research Area | Chemistry
; Science & Technology - Other Topics
; Materials Science
; Physics
|
| WOS Subject | Chemistry, Multidisciplinary
; Chemistry, Physical
; Nanoscience & Nanotechnology
; Materials Science, Multidisciplinary
; Physics, Applied
; Physics, Condensed Matter
|
| WOS Accession No | WOS:000936107600001
|
| Publisher | |
| ESI Research Field | MATERIALS SCIENCE
|
| Data Source | Web of Science
|
| Citation statistics |
Cited Times [WOS]:0
|
| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/490015 |
| Department | Department of Biomedical Engineering |
| Affiliation | 1.Nanyang Technol Univ, Sch Elect & Elect Engn, 50 Nanyang Ave, Singapore 639798, Singapore 2.Univ Technol Sydney, Inst Biomed Mat & Devices, Sch Math & Phys Sci, Broadway Ultimo, Sydney, NSW 2007, Australia 3.Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, State Key Lab High Performance Ceram & Superfine M, 1295 Dingxi Rd, Shanghai 200050, Peoples R China 4.Southern Univ Sci & Technol, Dept Biomed Engn, UTS SUSTech Joint Res Ctr Biomed Mat & Devices, Shenzhen 518055, Peoples R China |
| Corresponding Author Affilication | Department of Biomedical Engineering |
| Recommended Citation GB/T 7714 |
Fang, Guocheng,Chen, Yu-Cheng,Lu, Hongxu,et al. Advances in Spheroids and Organoids on a Chip[J]. ADVANCED FUNCTIONAL MATERIALS,2023.
|
| APA |
Fang, Guocheng,Chen, Yu-Cheng,Lu, Hongxu,&Jin, Dayong.(2023).Advances in Spheroids and Organoids on a Chip.ADVANCED FUNCTIONAL MATERIALS.
|
| MLA |
Fang, Guocheng,et al."Advances in Spheroids and Organoids on a Chip".ADVANCED FUNCTIONAL MATERIALS (2023).
|
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
; 
Edit Comment