中文版 | English
Title

Refractometric Imaging and Biodetection Empowered by Nanophotonics

Author
Corresponding AuthorShum, Perry Ping; Ma, Xingyi; Wang, Jiawei
Publication Years
2023
DOI
Source Title
ISSN
1863-8880
EISSN
1863-8899
Abstract
Advancing clinical and nonclinical diagnostic technologies is particularly crucial for improved preparedness for the next pandemic and other global healthcare challenges. To this end, marrying advanced microscopic imaging with chip-scale bioanalytical systems provides fresh modalities by analyzing signals of transmitted, reflected, or scattered light waves. This review brings clarity to the latest progress of refractometric imaging and biodetections on a chip, in which interferences and resonances as cornerstones of optics and plasmonics are breaking new ground. A vast range of nanophotonic and plasmonic transducers are discussed, ranging from planar films, nanoarrays, and waveguiding resonators to holistic designs. The augmented bioanalyses cover immunoassays, single-molecule analysis, and motion tracking of bacterial pathogens and cells. Compared to single-point spectroscopic measurements, imaging-empowered approaches are rapidly evolving with greatly promoted signal-noise ratio, spatial-temporal resolutions, multiplexability, and throughput, which can be accomplished in a compact cradle system with minimized bulky components in a spectrometer-free manner. Besides, advances in machine learning technologies applied for data analytics and transducer designs are highlighted. All in all, there are unlimited opportunities for new optical structures, principles, and ways of data retrieval to tap in, which will raise technological impacts on unveiling fundamental issues in life science and advancing global healthcare technologies.
© 2023 Wiley-VCH GmbH.
Indexed By
EI ; SCI
Language
English
SUSTech Authorship
Corresponding
Funding Project
The authors acknowledge fruitful discussions with Yuanzheng Ma and M'Madi Issimail Fahim El‐Kassim. J.W. gratefully acknowledges the support of the National Natural Science Foundation of China (Grant No. 62105080) and the GuangDong Basic and Applied Basic Research Foundation Regional Joint Fund (Grant No. 2020A1515110328). X.M. acknowledges the grants from Science and Technology Innovation Commission of Shenzhen (Nos. JCYJ20210324132815037 and GXWD20220818171934001), China Postdoctoral Science Foundation (No. 2017M621664), Department of Education of Guangdong Province (Nos. 2021KQNCX276 and 2022ZDZX2065), the Fundamental Research Funds for the Central Universities (Grant No. HIT.OCEF.2022040), Zhujiang Talents Programme (No. 2021QN02Y120), Qianjiang Talents Programme (No. QJD2002017), Taishan Industrial Experts Programme (No. TSCY202006001), and the provincial Science Foundation for the Excellent Youth Scholars (No. 2022HWYQ097).
WOS Accession No
WOS:000939486100001
Publisher
EI Accession Number
20230813623067
EI Keywords
Health care ; Learning systems ; Nanophotonics ; Quantum optics ; Spectrometers ; Taps ; Transducers
ESI Classification Code
Health Care:461.7 ; Small Tools, Unpowered:605.2 ; Data Processing and Image Processing:723.2 ; Light/Optics:741.1 ; Optical Devices and Systems:741.3 ; Quantum Theory; Quantum Mechanics:931.4
Data Source
EV Compendex
Citation statistics
Cited Times [WOS]:4
Document TypeJournal Article
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/519653
DepartmentDepartment of Electrical and Electronic Engineering
Affiliation
1.School of Electronic and Information Engineering, Harbin Institute of Technology, Guangdong, Shenzhen; 518055, China
2.Tsinghua Shenzhen International Graduate School and Tsinghua-Berkeley Shenzhen Institute, Tsinghua University, Shenzhen; 518055, China
3.Department of Electronic and Electrical Engineering, Southern University of Science and Technology, Shenzhen; 518055, China
4.School of Science, Harbin Institute of Technology, Guangdong, Shenzhen; 518055, China
Corresponding Author AffilicationDepartment of Electrical and Electronic Engineering
Recommended Citation
GB/T 7714
Sun, Shengqi,Wu, Lan,Geng, Zihan,et al. Refractometric Imaging and Biodetection Empowered by Nanophotonics[J]. Laser & Photonics Reviews,2023.
APA
Sun, Shengqi,Wu, Lan,Geng, Zihan,Shum, Perry Ping,Ma, Xingyi,&Wang, Jiawei.(2023).Refractometric Imaging and Biodetection Empowered by Nanophotonics.Laser & Photonics Reviews.
MLA
Sun, Shengqi,et al."Refractometric Imaging and Biodetection Empowered by Nanophotonics".Laser & Photonics Reviews (2023).
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