中文版 | English
Title

Mesoporous Silica Nanoparticles Induce Intracellular Peroxidation Damage of Phytophthora infestans: A New Type of Green Fungicide for Late Blight Control

Author
Corresponding AuthorChen, Zhi; Pan, Xiaohong
Publication Years
2022
DOI
Source Title
ISSN
0013-936X
EISSN
1520-5851
Abstract
Nanopesticides are considered to be a promising alternative strategy for enhancing bioactivity and delaying the development of pathogen resistance to pesticides. Here, a new type of nanosilica fungicide was proposed and demonstrated to control late blight by inducing intracellular peroxidation damage to Phytophthora infestans, the pathogen associated with potato late blight. Results indicated that the structural features of different silica nanoparticles were largely responsible for their antimicrobial activities. Mesoporous silica nanoparticles (MSNs) exhibited the highest antimicrobial activity with a 98.02% inhibition rate of P. infestans, causing oxidative stress responses and cell structure damage in P. infestans. For the first time, MSNs were found to selectively induce spontaneous excess production of intracellular reactive oxygen species in pathogenic cells, including hydroxyl radicals (•OH), superoxide radicals (•O2-), and singlet oxygen (1O2), leading to peroxidation damage in P. infestans. The effectiveness of MSNs was further tested in the pot experiments as well as leaf and tuber infection, and successful control of potato late blight was achieved with high plant compatibility and safety. This work provides new insights into the antimicrobial mechanism of nanosilica and highlights the use of nanoparticles for controlling late blight with green and highly efficient nanofungicides.
© 2023 American Chemical Society.
Keywords
URL[Source Record]
Indexed By
EI ; SCI
Language
English
SUSTech Authorship
Others
Funding Project
We are grateful to Prof. J.S. Zhan, W. Zhu, L.N. Yang, and F.F. Zhan for the grant of Phytophthora infestans, potato plants, and advice on experimental design. This work was financially supported by the National Key R&D Program of China (grant no. 2022 YFD1400700), the Natural Science Foundation of Fujian Province, China (2020J01522), the Fujian Agriculture and Forestry University Construction Project for Technological Innovation and Service System of the Tea Industry Chain (K1520005A03), and the Special Fund for Scientific and Technological Innovation of Fujian Agriculture and Forestry University (CXZX2019005S and CXZX2020024A).
WOS Research Area
Engineering ; Environmental Sciences & Ecology
WOS Subject
Engineering, Environmental ; Environmental Sciences
WOS Accession No
WOS:000964319600001
Publisher
EI Accession Number
20230913646893
EI Keywords
Fungicides ; Hydrophobicity ; Microorganisms ; Oxygen ; Silica nanoparticles
ESI Classification Code
Biology:461.9 ; Nanotechnology:761 ; Chemical Reactions:802.2 ; Chemical Products Generally:804 ; Organic Compounds:804.1 ; Physical Properties of Gases, Liquids and Solids:931.2
ESI Research Field
ENVIRONMENT/ECOLOGY
Data Source
EV Compendex
Citation statistics
Cited Times [WOS]:2
Document TypeJournal Article
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/519777
DepartmentSouthern University of Science and Technology
Affiliation
1.State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops & Key Lab of Biopesticide and Chemical Biology, Ministry of Education & Ministerial and Provincial Joint Innovation Centre for Safety Production of Cross-Strait Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fujian, Fuzhou; 350002, China
2.College of Resources and Environment, Fujian Agriculture and Forestry University, Fujian, Fuzhou; 350002, China
3.Southern University of Science and Technology, Guangdong, Shenzhen; 518055, China
Recommended Citation
GB/T 7714
Chen, Saili,Guo, Xueping,Zhang, Bintian,et al. Mesoporous Silica Nanoparticles Induce Intracellular Peroxidation Damage of Phytophthora infestans: A New Type of Green Fungicide for Late Blight Control[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2022.
APA
Chen, Saili.,Guo, Xueping.,Zhang, Bintian.,Nie, Danyue.,Rao, Wenhua.,...&Pan, Xiaohong.(2022).Mesoporous Silica Nanoparticles Induce Intracellular Peroxidation Damage of Phytophthora infestans: A New Type of Green Fungicide for Late Blight Control.ENVIRONMENTAL SCIENCE & TECHNOLOGY.
MLA
Chen, Saili,et al."Mesoporous Silica Nanoparticles Induce Intracellular Peroxidation Damage of Phytophthora infestans: A New Type of Green Fungicide for Late Blight Control".ENVIRONMENTAL SCIENCE & TECHNOLOGY (2022).
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