中文版 | English
Title

Hierarchical DNN with Heterogeneous Computing enabled High-Performance DNA Sequencing

Author
Corresponding AuthorMei Yan; Hao Yu
DOI
Publication Years
2022-11
Conference Name
Proc. 2022 IEEE 18th Asia Pacific Conf. Circuits Syst. (APCCAS)
ISBN
978-1-6654-5080-5
Source Title
Pages
35-40
Conference Date
2022-11
Conference Place
深圳
Abstract

DNA sequencing is a popular tool to demystify the
code of living organisms and is reforming the medical,
pharmaceutical and biotech industries. The Next-Generation
Sequencing (NGS) plays a vital role in high-throughput DNA
sequencing with massively parallel data generation.
Nevertheless, the massive amount of data imposes great
challenges for data analysis. It is arduous to reach a low error
rate for handling noisy and/or biased signals owing to the
imperfect biochemical reactions and imaging systems.
Furthermore, a homogeneous computing system lacks
computing power and memory bandwidth. Therefore, in this
work, a heterogeneous computing platform with a hierarchical
deep neural network sequencing pipeline is proposed to improve
the sequencing quality and increase processing speed.
Experiments demonstrate that the proposed work reached
higher effective throughput (12.18% more clusters found),
lower error rate (0.0175%), higher quality score (%Q30
99.27%), and 19% faster. The reported work empowers virus
detection, diseases diagnostic, and other potential biomedical
applications

Keywords
SUSTech Authorship
Corresponding
URL[Source Record]
Data Source
人工提交
PDF urlhttps://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=10090281
Citation statistics
Cited Times [WOS]:0
Document TypeConference paper
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/519915
DepartmentSUSTech Institute of Microelectronics
Affiliation
1.GeneSense Technology Inc., Shanghai 201210
2.School of Microelectronics, Southern University of Science and Technology
3.Ministry of Education Key Laboratory of RF Circuits and Systems, Hangzhou Dianzi University
Corresponding Author AffilicationSUSTech Institute of Microelectronics
Recommended Citation
GB/T 7714
Shaobo Luo,,Zhiyuan Xie,Gengxin Chen,et al. Hierarchical DNN with Heterogeneous Computing enabled High-Performance DNA Sequencing[C],2022:35-40.
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