| Title | Alkoxyphosphorane/Borane Cooperative Alkylations: A Frustrated Lewis Pair Version of the Mitsunobu Reaction |
| Author | |
| Corresponding Author | Liu, Liu Leo; Wu, Yile; Stephan, Douglas W. |
| Publication Years | 2023-03-01
|
| DOI | |
| Source Title | |
| ISSN | 0947-6539
|
| EISSN | 1521-3765
|
| Abstract | The combination of the alkoxyphosphoranes, Ph2P(OR)(O2C6Cl4) and the borane B(C6F5)(3) generates the zwitterions 3 which act as FLP to effect the alkylation of several nucleophiles affording C-C, C-N, C-H and C-Cl coupling products. A DFT study shows the reaction proceeds via an FLP activation pathway generating an alkoxyphosphonium intermediate which effects the alkylation of the nucleophiles, akin to the Mitsunobu reaction. |
| Keywords | |
| URL | [Source Record] |
| Indexed By | |
| Language | English
|
| SUSTech Authorship | Corresponding
|
| Funding Project | Ningbo Natural Science Foundation[2022J108]
; Scientific Research Grant of Ningbo University["215-432000282","422110973"]
; Ningbo Top Talent Project[215-432094250]
|
| WOS Research Area | Chemistry
|
| WOS Subject | Chemistry, Multidisciplinary
|
| WOS Accession No | WOS:000949017400001
|
| Publisher | |
| ESI Research Field | CHEMISTRY
|
| Data Source | Web of Science
|
| Citation statistics |
Cited Times [WOS]:0
|
| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/523904 |
| Department | Department of Chemistry |
| Affiliation | 1.Ningbo Univ, Inst Drug Discovery Technol, Ningbo 315211, Zhejiang, Peoples R China 2.Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Peoples R China 3.Southern Univ Sci & Technol, Guangdong Prov Key Lab Catalysis, Shenzhen 518055, Peoples R China 4.Univ Toronto, Dept Chem, 80 St George St, Toronto, ON M5S 3H6, Canada |
| Corresponding Author Affilication | Department of Chemistry; Southern University of Science and Technology |
| Recommended Citation GB/T 7714 |
Chen, Ting,Mei, Yanbo,Liu, Liu Leo,et al. Alkoxyphosphorane/Borane Cooperative Alkylations: A Frustrated Lewis Pair Version of the Mitsunobu Reaction[J]. CHEMISTRY-A EUROPEAN JOURNAL,2023.
|
| APA |
Chen, Ting,Mei, Yanbo,Liu, Liu Leo,Zhao, Yufen,Wu, Yile,&Stephan, Douglas W..(2023).Alkoxyphosphorane/Borane Cooperative Alkylations: A Frustrated Lewis Pair Version of the Mitsunobu Reaction.CHEMISTRY-A EUROPEAN JOURNAL.
|
| MLA |
Chen, Ting,et al."Alkoxyphosphorane/Borane Cooperative Alkylations: A Frustrated Lewis Pair Version of the Mitsunobu Reaction".CHEMISTRY-A EUROPEAN JOURNAL (2023).
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