| Title | Epitranscriptomics in the development, functions, and disorders of cancer stem cells |
| Author | |
| Corresponding Author | Guo, Jie |
| Publication Years | 2023-03-17
|
| DOI | |
| Source Title | |
| ISSN | 2234-943X
|
| Volume | 13 |
| Abstract | Biomolecular modifications play an important role in the development of life, and previous studies have investigated the role of DNA and proteins. In the last decade, with the development of sequencing technology, the veil of epitranscriptomics has been gradually lifted. Transcriptomics focuses on RNA modifications that affect gene expression at the transcriptional level. With further research, scientists have found that changes in RNA modification proteins are closely linked to cancer tumorigenesis, progression, metastasis, and drug resistance. Cancer stem cells (CSCs) are considered powerful drivers of tumorigenesis and key factors for therapeutic resistance. In this article, we focus on describing RNA modifications associated with CSCs and summarize the associated research progress. The aim of this review is to identify new directions for cancer diagnosis and targeted therapy. |
| Keywords | |
| URL | [Source Record] |
| Indexed By | |
| Language | English
|
| SUSTech Authorship | Others
|
| WOS Research Area | Oncology
|
| WOS Subject | Oncology
|
| WOS Accession No | WOS:000961284900001
|
| Publisher | |
| Data Source | Web of Science
|
| Citation statistics |
Cited Times [WOS]:0
|
| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/524063 |
| Department | Department of Biology 生命科学学院 |
| Affiliation | 1.Second Hosp Jilin Univ, Dept Tumor Radiotherapy, Changchun, Peoples R China 2.Southern Univ Sci & Technol, Sch Life Sci, Dept Biol, Shenzhen, Peoples R China |
| Recommended Citation GB/T 7714 |
Hao, Linlin,Zhang, Jian,Liu, Zhongshan,et al. Epitranscriptomics in the development, functions, and disorders of cancer stem cells[J]. FRONTIERS IN ONCOLOGY,2023,13.
|
| APA |
Hao, Linlin,Zhang, Jian,Liu, Zhongshan,Lin, Xia,&Guo, Jie.(2023).Epitranscriptomics in the development, functions, and disorders of cancer stem cells.FRONTIERS IN ONCOLOGY,13.
|
| MLA |
Hao, Linlin,et al."Epitranscriptomics in the development, functions, and disorders of cancer stem cells".FRONTIERS IN ONCOLOGY 13(2023).
|
| Files in This Item: | There are no files associated with this item. | |||||
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