| Title | Making small molecules in plants: A chassis for synthetic biology-based production of plant natural products |
| Author | |
| Corresponding Author | Huang，Ancheng C. |
| Publication Years | 2023-02-01
|
| DOI | |
| Source Title | |
| ISSN | 1672-9072
|
| EISSN | 1744-7909
|
| Volume | 65Issue:2Pages:417-443 |
| Abstract | Plant natural products have been extensively exploited in food, medicine, flavor, cosmetic, renewable fuel, and other industrial sectors. Synthetic biology has recently emerged as a promising means for the cost-effective and sustainable production of natural products. Compared with engineering microbes for the production of plant natural products, the potential of plants as chassis for producing these compounds is underestimated, largely due to challenges encountered in engineering plants. Knowledge in plant engineering is instrumental for enabling the effective and efficient production of valuable phytochemicals in plants, and also paves the way for a more sustainable future agriculture. In this manuscript, we briefly recap the biosynthesis of plant natural products, focusing primarily on industrially important terpenoids, alkaloids, and phenylpropanoids. We further summarize the plant hosts and strategies that have been used to engineer the production of natural products. The challenges and opportunities of using plant synthetic biology to achieve rapid and scalable production of high-value plant natural products are also discussed. |
| Keywords | |
| URL | [Source Record] |
| Indexed By | |
| Language | English
|
| SUSTech Authorship | First
; Corresponding
|
| WOS Accession No | WOS:000905247200001
|
| Scopus EID | 2-s2.0-85138576677
|
| Data Source | Scopus
|
| Citation statistics |
Cited Times [WOS]:4
|
| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/524219 |
| Department | SUSTech-Peking University National Institute of Plants and Food 生命科学学院 生命科学学院_生物系 |
| Affiliation | 1.Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes,Department of Biology,School of Life Sciences,SUSTech-PKU Institute of Plant and Food Science,Southern University of Science and Technology,Shenzhen,518055,China 2.Shenzhen Institutes of Advanced Technology (SIAT),the Chinese Academy of Sciences,Shenzhen,518055,China |
| First Author Affilication | SUSTech-Peking University National Institute of Plants and Food; Department of Biology; School of Life Sciences |
| Corresponding Author Affilication | SUSTech-Peking University National Institute of Plants and Food; Department of Biology; School of Life Sciences |
| First Author's First Affilication | SUSTech-Peking University National Institute of Plants and Food; Department of Biology; School of Life Sciences |
| Recommended Citation GB/T 7714 |
Liu，Xinyu,Zhang，Peijun,Zhao，Qiao,et al. Making small molecules in plants: A chassis for synthetic biology-based production of plant natural products[J]. Journal of Integrative Plant Biology,2023,65(2):417-443.
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| APA |
Liu，Xinyu,Zhang，Peijun,Zhao，Qiao,&Huang，Ancheng C..(2023).Making small molecules in plants: A chassis for synthetic biology-based production of plant natural products.Journal of Integrative Plant Biology,65(2),417-443.
|
| MLA |
Liu，Xinyu,et al."Making small molecules in plants: A chassis for synthetic biology-based production of plant natural products".Journal of Integrative Plant Biology 65.2(2023):417-443.
|
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