Title | Distinct chromatin signatures in the Arabidopsis male gametophyte |
Author | |
Corresponding Author | Xi,Chen; Zhe,Wu |
Joint first author | Danling,Zhu; Yi,Wen |
Publication Years | 2023-03-01
|
DOI | |
Source Title | |
ISSN | 1061-4036
|
EISSN | 1546-1718
|
Abstract | Epigenetic reprogramming in the germline contributes to the erasure of epigenetic inheritance across generations in mammals but remains poorly characterized in plants. Here we profiled histone modifications throughout Arabidopsis male germline development. We find that the sperm cell has widespread apparent chromatin bivalency, which is established by the acquisition of H3K27me3 or H3K4me3 at pre-existing H3K4me3 or H3K27me3 regions, respectively. These bivalent domains are associated with a distinct transcriptional status. Somatic H3K27me3 is generally reduced in sperm, while dramatic loss of H3K27me3 is observed at only similar to 700 developmental genes. The incorporation of the histone variant H3.10 facilitates the establishment of sperm chromatin identity without a strong impact on resetting of somatic H3K27me3. Vegetative nuclei harbor thousands of specific H3K27me3 domains at repressed genes, while pollination-related genes are highly expressed and marked by gene body H3K4me3. Our work highlights putative chromatin bivalency and restricted resetting of H3K27me3 at developmental regulators as key features in plant pluripotent sperm. |
URL | [Source Record] |
Indexed By | |
Language | English
|
Important Publications | NI Journal Papers
|
SUSTech Authorship | First
; 共同第一
; Corresponding
|
Funding Project | National Natural Science Foundation of China["32270369","31970277","32170348","2022A1515010505"]
; null[32070645]
; null[2016ZT06S172]
; null[JCYJ20210324104803009]
; null[JCYJ20190809141201671]
; null[20200925153455004]
; null[KYTDPT20181011104005]
; null[ZDSYS20200811144002008]
; null[2019KSYS006]
|
WOS Research Area | Genetics & Heredity
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WOS Subject | Genetics & Heredity
|
WOS Accession No | WOS:000971784400004
|
Publisher | |
ESI Research Field | MOLECULAR BIOLOGY & GENETICS
|
Data Source | Web of Science
|
Citation statistics |
Cited Times [WOS]:2
|
Document Type | Journal Article |
Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/527482 |
Department | SUSTech-Peking University National Institute of Plants and Food 生命科学学院 生命科学学院_生物系 |
Affiliation | 1.Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, Institute of Plant and Food Science, Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China. 2.Shenzhen Key Laboratory of Gene Regulation and Systems Biology, Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China 3.Center for Advanced Biotechnology and Medicine, Biological Mass Spectrometry Facility, Rutgers University, Piscataway, NJ, USA 4.State Key Laboratory of Protein and Plant Gene Research, Peking-Tsinghua Center for Life Sciences, College of Life Sciences, Peking University, Beijing, China |
First Author Affilication | SUSTech-Peking University National Institute of Plants and Food; Department of Biology; School of Life Sciences |
Corresponding Author Affilication | SUSTech-Peking University National Institute of Plants and Food; Department of Biology; School of Life Sciences |
First Author's First Affilication | SUSTech-Peking University National Institute of Plants and Food; Department of Biology; School of Life Sciences |
Recommended Citation GB/T 7714 |
Danling,Zhu,Yi,Wen,Wanyue,Yao,et al. Distinct chromatin signatures in the Arabidopsis male gametophyte[J]. NATURE GENETICS,2023.
|
APA |
Danling,Zhu.,Yi,Wen.,Wanyue,Yao.,Haiyan,Zheng.,Sixian,Zhou.,...&Zhe,Wu.(2023).Distinct chromatin signatures in the Arabidopsis male gametophyte.NATURE GENETICS.
|
MLA |
Danling,Zhu,et al."Distinct chromatin signatures in the Arabidopsis male gametophyte".NATURE GENETICS (2023).
|
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