中文版 | English
Title

Distinct chromatin signatures in the Arabidopsis male gametophyte

Author
Corresponding AuthorXi,Chen; Zhe,Wu
Joint first authorDanling,Zhu; Yi,Wen
Publication Years
2023-03-01
DOI
Source Title
ISSN
1061-4036
EISSN
1546-1718
Abstract
Epigenetic reprogramming in the germline contributes to the erasure of epigenetic inheritance across generations in mammals but remains poorly characterized in plants. Here we profiled histone modifications throughout Arabidopsis male germline development. We find that the sperm cell has widespread apparent chromatin bivalency, which is established by the acquisition of H3K27me3 or H3K4me3 at pre-existing H3K4me3 or H3K27me3 regions, respectively. These bivalent domains are associated with a distinct transcriptional status. Somatic H3K27me3 is generally reduced in sperm, while dramatic loss of H3K27me3 is observed at only similar to 700 developmental genes. The incorporation of the histone variant H3.10 facilitates the establishment of sperm chromatin identity without a strong impact on resetting of somatic H3K27me3. Vegetative nuclei harbor thousands of specific H3K27me3 domains at repressed genes, while pollination-related genes are highly expressed and marked by gene body H3K4me3. Our work highlights putative chromatin bivalency and restricted resetting of H3K27me3 at developmental regulators as key features in plant pluripotent sperm.
URL[Source Record]
Indexed By
Language
English
Important Publications
NI Journal Papers
SUSTech Authorship
First ; 共同第一 ; Corresponding
Funding Project
National Natural Science Foundation of China["32270369","31970277","32170348","2022A1515010505"] ; null[32070645] ; null[2016ZT06S172] ; null[JCYJ20210324104803009] ; null[JCYJ20190809141201671] ; null[20200925153455004] ; null[KYTDPT20181011104005] ; null[ZDSYS20200811144002008] ; null[2019KSYS006]
WOS Research Area
Genetics & Heredity
WOS Subject
Genetics & Heredity
WOS Accession No
WOS:000971784400004
Publisher
ESI Research Field
MOLECULAR BIOLOGY & GENETICS
Data Source
Web of Science
Citation statistics
Cited Times [WOS]:2
Document TypeJournal Article
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/527482
DepartmentSUSTech-Peking University National Institute of Plants and Food
生命科学学院
生命科学学院_生物系
Affiliation
1.Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, Institute of Plant and Food Science, Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China.
2.Shenzhen Key Laboratory of Gene Regulation and Systems Biology, Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China
3.Center for Advanced Biotechnology and Medicine, Biological Mass Spectrometry Facility, Rutgers University, Piscataway, NJ, USA
4.State Key Laboratory of Protein and Plant Gene Research, Peking-Tsinghua Center for Life Sciences, College of Life Sciences, Peking University, Beijing, China
First Author AffilicationSUSTech-Peking University National Institute of Plants and Food;  Department of Biology;  School of Life Sciences
Corresponding Author AffilicationSUSTech-Peking University National Institute of Plants and Food;  Department of Biology;  School of Life Sciences
First Author's First AffilicationSUSTech-Peking University National Institute of Plants and Food;  Department of Biology;  School of Life Sciences
Recommended Citation
GB/T 7714
Danling,Zhu,Yi,Wen,Wanyue,Yao,et al. Distinct chromatin signatures in the Arabidopsis male gametophyte[J]. NATURE GENETICS,2023.
APA
Danling,Zhu.,Yi,Wen.,Wanyue,Yao.,Haiyan,Zheng.,Sixian,Zhou.,...&Zhe,Wu.(2023).Distinct chromatin signatures in the Arabidopsis male gametophyte.NATURE GENETICS.
MLA
Danling,Zhu,et al."Distinct chromatin signatures in the Arabidopsis male gametophyte".NATURE GENETICS (2023).
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