中文版 | English
Title

司美格鲁肽治疗肢端肥大症致继发性糖尿病1例

Alternative Title
Application of semaglutide in the treatment of diabetes secondary to acromegaly: a case report
Author
Publication Years
2022
DOI
Source Title
ISSN
1674-5809
Volume14Issue:Z1Pages:141-143
Abstract
回顾性分析1例在深圳市人民医院内分泌科就诊的肢端肥大症致继发性糖尿病患者使用司美格鲁肽治疗的诊疗过程并进行文献复习。患者为55岁男性,因“发现肢端肥大23年,血糖升高19年”入院,患者明确诊断肢端肥大症、继发性糖尿病及肥胖症。垂体生长激素瘤经历手术后复发、伽马刀及生长抑素治疗,生长激素及胰岛素样生长因子-1已达标,予二甲双胍0.5 g、3次/d,阿卡波糖50 mg、3次/d联合甘精胰岛素36 U睡前控制血糖,血糖不达标,予调整降糖方案为司美格鲁肽1 mg、1次/周联合二甲双胍0.5 g、3次/d后血糖控制良好,体重下降8 kg,且未出现明显不良反应,患者满意。司美格鲁肽是一种新型长效胰高糖素样肽-1受体激动剂,以葡萄糖浓度依赖的方式刺激胰岛素分泌、抑制胰高糖素分泌,并能够延缓胃排空,通过中枢性的食欲抑制来减少进食量,从而达到降糖减重的作用,并且每周1次的用药方式大大提高了患者的用药依从性。
Keywords
URL[Source Record]
Language
Chinese
SUSTech Authorship
First
Data Source
WanFang
WanFangID
zhtnb2022Z1036
Citation statistics
Cited Times [WOS]:0
Document TypeJournal Article
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/531408
DepartmentShenzhen People's Hospital
Affiliation
深圳市人民医院 暨南大学第二临床医学院 南方科技大学第一附属医院内分泌科,深圳 518020
First Author AffilicationShenzhen People's Hospital
First Author's First AffilicationShenzhen People's Hospital
Recommended Citation
GB/T 7714
乐颖,薛萌. 司美格鲁肽治疗肢端肥大症致继发性糖尿病1例[J]. 中华糖尿病杂志,2022,14(Z1):141-143.
APA
乐颖,&薛萌.(2022).司美格鲁肽治疗肢端肥大症致继发性糖尿病1例.中华糖尿病杂志,14(Z1),141-143.
MLA
乐颖,et al."司美格鲁肽治疗肢端肥大症致继发性糖尿病1例".中华糖尿病杂志 14.Z1(2022):141-143.
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