南方科技大学知识苑(SUSTech KC): 一种软硬可调的液态金属神经电极及其制备方法和应用

Title	一种软硬可调的液态金属神经电极及其制备方法和应用
Alternative Title	Hardness-adjustable liquid metal neural electrode and preparation method and application thereof
Author	蒋兴宇; 董瑞华
First Inventor	蒋兴宇
Original applicant	南方科技大学
First applicant	南方科技大学
Address of First applicant	518055 广东省深圳市南山区西丽学苑大道1088号
Current applicant	南方科技大学
Address of Current applicant	518055 广东省深圳市南山区西丽学苑大道1088号 (广东,深圳,南山区)
First Current Applicant	南方科技大学
Address of First Current Applicant	518055 广东省深圳市南山区西丽学苑大道1088号 (广东,深圳,南山区)
Application Number	CN202011414621.6
Application Date	2020-12-04
Open (Notice) Number	CN112545523A
Date Available	2021-03-26
Status of Patent	实质审查
Legal Date	2021-04-13
Subtype	发明申请
SUSTech Authorship	First
Abstract	本发明涉及一种软硬可调的液态金属神经电极及其制备方法和应用，所述液态金属神经电极包括柔性高分子基底、导电层以及绝缘层，所述导电层包括液态金属导线以及设置在所述液态金属导线端部的电极位点；所述导电层嵌于所述柔性高分子基底中，所述绝缘层覆盖所述液态金属导线；所述液态金属的熔点为15‑35℃。本发明提供的神经电极既可以实现特定脑区的深度植入，又能在植入后具有优异的柔性，降低周围脑组织的损伤，同时具有良好的生物相容性和拉伸性能，可以保证脑电信号监测的稳定性和可靠性。
Other Abstract	The invention relates to a hardness-adjustable liquid metal neural electrode and a preparation method and application thereof. The liquid metal neural electrode comprises a flexible polymer substrate,a conductive layer and an insulating layer, wherein the conductive layer comprises a liquid metal wire and an electrode site arranged at the end of the liquid metal wire; the conductive layer is embedded in the flexible polymer substrate, and the insulating layer covers the liquid metal wire; and the melting point of the liquid metal is 15-35 DEG C. The neural electrode provided by the inventionnot only can realize deep implantation of a specific brain region, but also has excellent flexibility after implantation, reduces the damage of surrounding brain tissues, has good biocompatibility andtensile property, and can ensure the stability and reliability of electroencephalogram signal monitoring.
CPC Classification Number	A61B5/6868 ; H01B5/14 ; H01B1/02 ; H01B13/00 ; A61B2562/0209 ; A61B2562/125
IPC Classification Number	A61B5/294 ; A61B5/263 ; A61B5/388 ; A61B5/271 ; A61B5/273 ; H01B1/02 ; H01B5/14 ; H01B13/00
INPADOC Legal Status	（ENTRY INTO FORCE OF REQUEST FOR SUBSTANTIVE EXAMINATION）[2021-04-13][CN]
INPADOC Patent Family Count	1
Extended Patent Family Count	1
Priority date	2020-12-04
Patent Agent	潘登
Agency	北京品源专利代理有限公司
URL	[Source Record]
Data Source	PatSnap
Document Type	Patent
Identifier	http://kc.sustech.edu.cn/handle/2SGJ60CL/532111
Department	Department of Biomedical Engineering
Recommended Citation GB/T 7714	蒋兴宇,董瑞华. 一种软硬可调的液态金属神经电极及其制备方法和应用.

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