南方科技大学知识苑(SUSTech KC): 基于旋转平台的病理切片成像装置及病理切片成像方法

Title	基于旋转平台的病理切片成像装置及病理切片成像方法
Alternative Title	Pathological section imaging device and pathological section imaging method based on rotating platform
Author	郭智勇; 杨志超
First Inventor	郭智勇
Original applicant	南方科技大学
First applicant	南方科技大学
Address of First applicant	518055 广东省深圳市南山区西丽学苑大道1088号
Current applicant	南方科技大学
Address of Current applicant	518055 广东省深圳市南山区西丽学苑大道1088号 (广东,深圳,南山区)
First Current Applicant	南方科技大学
Address of First Current Applicant	518055 广东省深圳市南山区西丽学苑大道1088号 (广东,深圳,南山区)
Application Number	CN202011059174.7
Application Date	2020-09-30
Open (Notice) Number	CN112229841A
Date Available	2021-01-15
Status of Patent	实质审查
Legal Date	2021-02-02
Subtype	发明申请
SUSTech Authorship	First
Abstract	本发明公开了一种基于旋转平台的病理切片成像装置及病理切片成像方法。病理切片成像装置包括旋转平台、光源组件和成像组件。旋转平台包括驱动件和旋转卡盘，驱动件驱动旋转卡盘旋转，旋转卡盘用于承载装有样品的载玻片，载玻片和样品跟随旋转卡盘转动以使样品的一部分处于预设空间区域。光源组件用于对样品进行照明。成像组件在旋转卡盘旋转时获得预设空间区域的多帧图像，并合成图像。本发明基于旋转平台的病理切片成像装置及病理切片成像方法，采用转盘结构承载多片曲面载玻片的样品，应用线状共聚焦技术，配合多片样品旋转运动进行扫描成像，扫描过程可实现无需调焦的高速病理切片扫描，具有成像信噪比高，成像速度快的优势。
Other Abstract	The invention discloses a pathological section imaging device and a pathological section imaging method based on a rotating platform. The pathological section imaging device comprises a rotating platform, a light source assembly and an imaging assembly. The rotating platform comprises a driving part and a rotating chuck, the driving part drives the rotating chuck to rotate, the rotating chuck is used for bearing a glass slide containing a sample, and the glass slide and the sample rotate along with the rotating chuck so that one part of the sample can be located in a preset space area. The light source assembly is used for illuminating the sample. The imaging assembly obtains multiple frames of images of a preset space area when the rotary chuck rotates and synthesizes the images. According to the pathological section imaging device and the pathological section imaging method based on the rotating platform, the samples of the curved glass slides are borne by adopting a turntable structure, the linear confocal technology is applied, scanning imaging is carried out in cooperation with rotating movement of the samples, high-speed pathological section scanning without focusing can be achieved in the scanning process, and the pathological section imaging device and the pathological section imaging method have the advantages of being high in imaging signal-to-noise ratio, and being fast in imaging speed.
CPC Classification Number	G01N21/86 ; G01N2021/8609 ; G01N2021/8654
IPC Classification Number	G01N21/86
INPADOC Legal Status	（ENTRY INTO FORCE OF REQUEST FOR SUBSTANTIVE EXAMINATION）[2021-02-02][CN]
INPADOC Patent Family Count	1
Extended Patent Family Count	1
Priority date	2020-09-30
Patent Agent	邵泳城
Agency	北京清亦华知识产权代理事务所(普通合伙)
URL	[Source Record]
Data Source	PatSnap
Document Type	Patent
Identifier	http://kc.sustech.edu.cn/handle/2SGJ60CL/532208
Department	Department of Biomedical Engineering
Recommended Citation GB/T 7714	郭智勇,杨志超. 基于旋转平台的病理切片成像装置及病理切片成像方法.

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