| Title | 一种地诺帕明及其中间体的制备方法 |
| Alternative Title | Denopamine and preparation method of intermediate of denopamine
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| Author | |
| First Inventor | 马保德
|
| Original applicant | 南方科技大学
|
| First applicant | 南方科技大学
|
| Address of First applicant | 518055 广东省深圳市南山区西丽学苑大道1088号
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| Current applicant | 南方科技大学
|
| Address of Current applicant | 518055 广东省深圳市南山区西丽学苑大道1088号 (广东,深圳,南山区)
|
| First Current Applicant | 南方科技大学
|
| Address of First Current Applicant | 518055 广东省深圳市南山区西丽学苑大道1088号 (广东,深圳,南山区)
|
| Application Number | CN201910901603.1
|
| Application Date | 2019-09-23
|
| Open (Notice) Number | CN110590583A
|
| Date Available | 2019-12-20
|
| Status of Patent | 实质审查
|
| Legal Date | 2020-01-14
|
| Subtype | 发明申请
|
| SUSTech Authorship | First
|
| Abstract | 本发明公开了一种地诺帕明及其中间体的制备方法，具体为通过Ir/f‑amphox催化不对称氢化制备地诺帕明的方法。该方法步骤简单，操作简便，条件温和，可以高效不对称氢化合成地诺帕明，催化剂用量可以仅为0.002mol％(S/C＝50,000)，具有巨大的工业应用价值。 |
| Other Abstract | The invention discloses denopamine and a preparation method of an intermediate of denopamine, and particularly provides a method for preparing denopamine by Ir/f-amphox catalytic asymmetric hydrogenation. According to the method, steps are simple, operation is simple and convenient, conditions are mild, denopamine can be synthesized efficiently by asymmetric hydrogenation, the dosage of a catalystcan only be 0.002 mol%(S/C=50,000), and the method has huge industrial application value. |
| CPC Classification Number | C07C221/00
; C07C213/08
; B01J31/2404
; B01J31/2295
; C07B53/00
; B01J2531/827
; B01J2531/842
; B01J2231/643
; C07B2200/07
|
| IPC Classification Number | C07C221/00
; C07C225/16
; C07C213/08
; C07C217/60
; B01J31/24
; C07B53/00
|
| INPADOC Legal Status | （ENTRY INTO FORCE OF REQUEST FOR SUBSTANTIVE EXAMINATION）[2020-01-14][CN]
|
| INPADOC Patent Family Count | 1
|
| Extended Patent Family Count | 1
|
| Priority date | 2019-09-23
|
| Patent Agent | 曾敬
|
| Agency | 深圳市创富知识产权代理有限公司
|
| URL | [Source Record] |
| Data Source | PatSnap
|
| Document Type | Patent |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/532930 |
| Department | School of Innovation and Entrepreneurship 理学院 |
| Recommended Citation GB/T 7714 |
马保德,邵攀霖,吴超,等. 一种地诺帕明及其中间体的制备方法.
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| Files in This Item: | There are no files associated with this item. | |||||
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