Title | 催化剂及其制备方法和手性醇类化合物的制备方法 |
Alternative Title | Catalyst, preparation method thereof and preparation method of chiral alcohol compounds
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Author | |
First Inventor | 邢详友
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Original applicant | 南方科技大学
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First applicant | 南方科技大学
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Address of First applicant | 518055 广东省深圳市南山区西丽镇学苑大道1088号南方科技大学
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Current applicant | 南方科技大学
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Address of Current applicant | 518055 广东省深圳市南山区西丽镇学苑大道1088号南方科技大学 (广东,深圳,南山区)
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First Current Applicant | 南方科技大学
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Address of First Current Applicant | 518055 广东省深圳市南山区西丽镇学苑大道1088号南方科技大学 (广东,深圳,南山区)
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Application Number | CN201910608777.9
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Application Date | 2019-07-05
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Open (Notice) Number | CN110526944A
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Date Available | 2019-12-03
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Status of Patent | 实质审查
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Legal Date | 2019-12-27
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Subtype | 发明申请
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SUSTech Authorship | First
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Abstract | 本发明涉及一种催化剂及其制备方法和手性醇类化合物的制备方法。上述催化剂具有如下结构通式:其中,多个R1分别独立地选自芳香族基团和取代芳香族基团中的一种;R2选自‑CH3、‑CH2CH3、‑CH2CH2CH3、‑CH(CH3)2、‑C(CH3)3、‑CH2(CH2)2CH3、环戊基及环己基中的一种;R3选自氢、‑C6H5、3,5‑(C(CH3)3)2‑C6H3‑、3,4,5‑F3‑C6H2‑、3,5‑(CF3)2‑C6H3‑及5‑OMe‑C6H4‑中的一种;R5选自‑CH2CH2‑、‑CH2CH2CH2‑、‑CH2(CH2)2CH2‑及‑C6H4‑中的一种。上述催化剂的催化活性高,且能够用于催化酮类化合物不对称合成。 |
Other Abstract | The invention relates to a catalyst, a preparation method thereof and a preparation method of chiral alcohol compounds. The catalyst has a structural general formula shown in the specification, wherein a plurality of R1 is one independently selected from an aromatic group and a substituted aromatic group; R2 is one selected from the group consisting of -CH3,-CH2CH3, -CH2CH2CH3, -CH(CH3)2, -C(CH3)3, -CH2(CH2)2CH3, cyclopentyl and cyclohexyl; R3 is one selected from the group consisting of hydrogen, -C6H5, 3,5-(C(CH3)3)2-C6H3-, 3,4,5-F3-C6H2-, 3,5-(CF3)2-C6H3- and 5-OMe-C6H4-; and R5 is one selected from the group consisting of -CH2CH2-, -CH2CH2CH2-, -CH2(CH2)2CH2- and -C6H4-. The catalyst provided by the invention has high catalytic activity and can be used to catalyze asymmetric synthesisof ketone compounds. |
CPC Classification Number | C07F15/0053
; B01J31/249
; C07B53/00
; C07D213/30
; C07D209/12
; C07C29/145
; C07B2200/07
; C07C33/025
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IPC Classification Number | C07F15/00
; B01J31/24
; C07B53/00
; C07D213/30
; C07D209/12
; C07C29/145
; C07C33/025
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INPADOC Legal Status | (CHANGE OF INVENTOR OR DESIGNER INFORMATION)[2020-04-24][CN]
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INPADOC Patent Family Count | 1
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Extended Patent Family Count | 1
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Priority date | 2019-07-05
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Patent Agent | 潘霞
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Agency | 广州华进联合专利商标代理有限公司
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URL | [Source Record] |
Data Source | PatSnap
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Document Type | Patent |
Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/534533 |
Department | Shenzhen Grubbs Institute |
Recommended Citation GB/T 7714 |
邢详友,徐晨,潘玉鹏,等. 催化剂及其制备方法和手性醇类化合物的制备方法.
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