中文版 | English
Title

催化剂及其制备方法和手性醇类化合物的制备方法

Alternative Title
Catalyst, preparation method thereof and preparation method of chiral alcohol compounds
Author
First Inventor
邢详友
Original applicant
南方科技大学
First applicant
南方科技大学
Address of First applicant
518055 广东省深圳市南山区西丽镇学苑大道1088号南方科技大学
Current applicant
南方科技大学
Address of Current applicant
518055 广东省深圳市南山区西丽镇学苑大道1088号南方科技大学 (广东,深圳,南山区)
First Current Applicant
南方科技大学
Address of First Current Applicant
518055 广东省深圳市南山区西丽镇学苑大道1088号南方科技大学 (广东,深圳,南山区)
Application Number
CN201910608777.9
Application Date
2019-07-05
Open (Notice) Number
CN110526944A
Date Available
2019-12-03
Status of Patent
实质审查
Legal Date
2019-12-27
Subtype
发明申请
SUSTech Authorship
First
Abstract
本发明涉及一种催化剂及其制备方法和手性醇类化合物的制备方法。上述催化剂具有如下结构通式:其中,多个R1分别独立地选自芳香族基团和取代芳香族基团中的一种;R2选自‑CH3、‑CH2CH3、‑CH2CH2CH3、‑CH(CH3)2、‑C(CH3)3、‑CH2(CH2)2CH3、环戊基及环己基中的一种;R3选自氢、‑C6H5、3,5‑(C(CH3)3)2‑C6H3‑、3,4,5‑F3‑C6H2‑、3,5‑(CF3)2‑C6H3‑及5‑OMe‑C6H4‑中的一种;R5选自‑CH2CH2‑、‑CH2CH2CH2‑、‑CH2(CH2)2CH2‑及‑C6H4‑中的一种。上述催化剂的催化活性高,且能够用于催化酮类化合物不对称合成。
Other Abstract
The invention relates to a catalyst, a preparation method thereof and a preparation method of chiral alcohol compounds. The catalyst has a structural general formula shown in the specification, wherein a plurality of R1 is one independently selected from an aromatic group and a substituted aromatic group; R2 is one selected from the group consisting of -CH3,-CH2CH3, -CH2CH2CH3, -CH(CH3)2, -C(CH3)3, -CH2(CH2)2CH3, cyclopentyl and cyclohexyl; R3 is one selected from the group consisting of hydrogen, -C6H5, 3,5-(C(CH3)3)2-C6H3-, 3,4,5-F3-C6H2-, 3,5-(CF3)2-C6H3- and 5-OMe-C6H4-; and R5 is one selected from the group consisting of -CH2CH2-, -CH2CH2CH2-, -CH2(CH2)2CH2- and -C6H4-. The catalyst provided by the invention has high catalytic activity and can be used to catalyze asymmetric synthesisof ketone compounds.
CPC Classification Number
C07F15/0053 ; B01J31/249 ; C07B53/00 ; C07D213/30 ; C07D209/12 ; C07C29/145 ; C07B2200/07 ; C07C33/025
IPC Classification Number
C07F15/00 ; B01J31/24 ; C07B53/00 ; C07D213/30 ; C07D209/12 ; C07C29/145 ; C07C33/025
INPADOC Legal Status
(CHANGE OF INVENTOR OR DESIGNER INFORMATION)[2020-04-24][CN]
INPADOC Patent Family Count
1
Extended Patent Family Count
1
Priority date
2019-07-05
Patent Agent
潘霞
Agency
广州华进联合专利商标代理有限公司
URL[Source Record]
Data Source
PatSnap
Document TypePatent
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/534533
DepartmentShenzhen Grubbs Institute
Recommended Citation
GB/T 7714
邢详友,徐晨,潘玉鹏,等. 催化剂及其制备方法和手性醇类化合物的制备方法.
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