南方科技大学知识苑(SUSTech KC): 即用式聚丙烯酸氟化银防龋齿涂膏和使用方法及工具

Title	即用式聚丙烯酸氟化银防龋齿涂膏和使用方法及工具
Alternative Title	Ready-to-use polyacrylic acid silver fluoride caries prevention paste and use method and tool
Author	王岩松; 唐斌
First Inventor	王岩松
Original applicant	南方科技大学
First applicant	南方科技大学
Address of First applicant	518055 广东省深圳市南山区桃源街道学苑大道1088号
Current applicant	南方科技大学
Address of Current applicant	518055 广东省深圳市南山区桃源街道学苑大道1088号 (广东,深圳,南山区)
First Current Applicant	南方科技大学
Address of First Current Applicant	518055 广东省深圳市南山区桃源街道学苑大道1088号 (广东,深圳,南山区)
Application Number	CN202210896988.9
Application Date	2022-07-28
Open (Notice) Number	CN115350098A
Date Available	2022-11-18
Status of Patent	实质审查
Legal Date	2022-12-06
Subtype	发明申请
SUSTech Authorship	First
Abstract	本发明公开了一种即用式聚丙烯酸氟化银防龋齿涂膏和使用方法及工具；即用式聚丙烯酸氟化银防龋齿涂膏按其成品重量来计算，需使用以下重量比例的原材料：5‑10份的二甲基亚砜，35‑40份的氟化银，10‑15份的聚丙烯酸，15‑20份的甘油，3‑5份的玉米醇溶蛋白和0.1‑1份的甘草查尔酮A；制作过程中，需要使用适量的无水乙醇，作为整个凝胶体系的溶剂；甘油和二甲基亚砜用于改变凝胶润滑和稳定性；玉米醇溶蛋白用于负载甘草查尔酮，调节pH值以形成均匀凝胶体系。本发明采用了玉米醇溶蛋白和中药多糖，改善了牙周微环境，使抗菌修复效果更好。且减小了胺带来的刺激性，增强了可操作性，且使产品的保质期更长。
Other Abstract	The invention discloses a ready-to-use polyacrylic acid silver fluoride caries prevention paste and a use method and tool thereof. The ready-to-use polyacrylic acid silver fluoride caries prevention paste needs to be prepared from the following raw materials in parts by weight according to the weight of a finished product: 5 to 10 parts of dimethyl sulfoxide, 35 to 40 parts of silver fluoride, 10 to 15 parts of polyacrylic acid, 15 to 20 parts of glycerol, 3 to 5 parts of zein and 0.1 to 1 part of licochalcone A; in the preparation process, a proper amount of absolute ethyl alcohol needs to be used as a solvent of the whole gel system; the glycerol and the dimethyl sulfoxide are used for changing the lubrication and the stability of the gel; the zein is used for loading licochalcone, and the pH value is adjusted to form a uniform gel system. The zein and the traditional Chinese medicine polysaccharide are adopted, the periodontal microenvironment is improved, and the antibacterial repairing effect is better. And moreover, the irritation caused by amine is reduced, the operability is enhanced, and the shelf life of the product is longer.
IPC Classification Number	A61K6/20 ; A61K6/887 ; A61K6/80 ; A61K6/60 ; A61C19/06
INPADOC Legal Status	（ENTRY INTO FORCE OF REQUEST FOR SUBSTANTIVE EXAMINATION）[2022-12-06][CN]
INPADOC Patent Family Count	1
Extended Patent Family Count	1
Priority date	2022-07-28
Patent Agent	曾敬
Agency	深圳市创富知识产权代理有限公司
URL	[Source Record]
Data Source	PatSnap
Document Type	Patent
Identifier	http://kc.sustech.edu.cn/handle/2SGJ60CL/534581
Department	Department of Biomedical Engineering
Recommended Citation GB/T 7714	王岩松,唐斌. 即用式聚丙烯酸氟化银防龋齿涂膏和使用方法及工具.

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